Results 1 to 10 of about 86,895 (235)

Reassessing Schistosoma worms: the overlooked role in host pathology and disease elimination [PDF]

open access: yesInfectious Diseases of Poverty
Background Schistosomiasis, a neglected tropical disease, remains a pressing global health challenge, hindering progress toward achievement of the Sustainable Development Goals (SDGs) in endemic regions.
Haoran Zhong   +3 more
doaj   +2 more sources

Epidemiological Trends and Progress in Schistosomiasis Elimination in Saudi Arabia (2021–2023): Implications for Neglected Tropical Disease Control [PDF]

open access: yesJournal of Epidemiology and Global Health
Schistosomiasis, a frequently overlooked parasitic disease, affects individuals worldwide. A comprehensive population-based observational study was conducted to assess the prevalence of schistosomiasis among both Saudi and non-Saudi residents.
Mawahib Ahmed, Basmah Alharbi
doaj   +2 more sources

Schistosomiasis [PDF]

open access: yesThe Lancet, 2018
AbstractSchistosomiasis is a parasitic disease that affects millions of people in 78 countries, where it is held responsible for considerable morbidity and mortality. It is caused by a blood fluke, which provokes an immunological response to hundreds of its antigens.
McManus, D. P.   +5 more
  +9 more sources

miR-181a regulates the host immune response against Schistosoma japonicum infection through the TLR4 receptor pathway

open access: yesParasites & Vectors, 2021
Background Schistosomiasis japonica is a serious zoonotic parasitic disease. Preliminary studies have shown that the expression of microRNA-181a (miR-181a) in the liver, lung and spleen tissues of susceptible host BALB/c mice and resistant host reed vole
Yixiao Tang   +8 more
doaj   +1 more source

Sja-Let-7 Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in a Mouse Model via Col1α2

open access: yesBiology, 2023
Liver fibrosis (LF) is a chronic progressive disease with no definitive treatment. The aim of this study was to assess helminth-derived molecules as potential therapeutic targets to prevent or reverse LF.
Haoran Zhong   +7 more
doaj   +1 more source

Characterisation and preliminary functional analysis of N-acetyltransferase 13 from Schistosoma japonicum

open access: yesBMC Veterinary Research, 2021
Background N-acetyltransferase 13 (NAT13) is a probable catalytic component of the ARD1A-NARG1 complex possessing alpha (N-terminal) acetyltransferase activity.
Yalan Tang   +12 more
doaj   +1 more source

Molecular and functional characterization of Schistosoma japonicum annexin A13

open access: yesVeterinary Research, 2023
Schistosomiasis is a neglected tropical disease that affects humans and animals in tropical and subtropical regions worldwide. Schistosome eggs are responsible for the pathogenesis and transmission of schistosomiasis, thus reducing egg production is ...
Haoran Zhong   +11 more
doaj   +1 more source

From Inflammation to Fibrosis: Novel Insights into the Roles of High Mobility Group Protein Box 1 in Schistosome-Induced Liver Damage

open access: yesPathogens, 2022
Schistosomiasis is a chronic helminthic disease of both humans and animals and the second most prevalent parasitic disease after malaria. Through a complex migration process, schistosome eggs trapped in the liver can lead to the formation of granulomas ...
Haoran Zhong   +4 more
doaj   +1 more source

The Dynamics of Hepatic Fibrosis Related to Schistosomiasis and Its Risk Factors in a Cohort of China

open access: yesPathogens, 2021
China has had a long history against schistosomiasis japonica. The most serious prognosis of chronic schistosome infection is hepatic fibrosis, which develops into advanced schistosomiasis if the process is not effectively controlled.
Fei Hu   +9 more
doaj   +1 more source

Spatio-temporal variations of emerging sites infested with schistosome-transmitting Oncomelania hupensis in Hunan Province, China, 1949–2016

open access: yesParasites & Vectors, 2021
Background Constant emerging sites infested with Oncomelania hupensis (O. hupensis) impede the goal realization of eliminating schistosomiasis. The study assessed the spatial and temporal distributions of new Oncomelania snail habitats in Hunan Province ...
Shengming Li   +13 more
doaj   +1 more source

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