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Praziquantel Pretreatment Reduces Schistosoma japonicum Infection in Mice by Targeting Immature Worm Stages [PDF]
Tropical Medicine and Infectious DiseaseSchistosomiasis remains a significant public health concern, with Schistosoma japonicum infection endemic in certain regions of Asia. Praziquantel (PZQ), primarily known as an effective therapeutic agent, has recently shown potential as a prophylactic ...
Xiang Gui +7 more
doaj +2 more sources
Current Tropical Medicine Reports, 2023 Purposeof Review The purpose of this review is to provide an overview of the burden of schistosomiasis in the European continent. It discusses three subjects: the endemic forms of non-human schistosomiasis in Europe; the introduction of transmission of ...
A. Gabrielli, Amadou Garba Djirmay
semanticscholar +1 more source
Schistosomiasis with a Focus on Africa
Tropical Medicine and Infectious Disease, 2021 Schistosomiasis is a common neglected tropical disease of impoverished people and livestock in many developing countries in tropical Africa, the Middle East, Asia, and Latin America.
O. Aula +3 more
semanticscholar +1 more source
Parasites & Vectors, 2021 Background Schistosomiasis japonica is a serious zoonotic parasitic disease. Preliminary studies have shown that the expression of microRNA-181a (miR-181a) in the liver, lung and spleen tissues of susceptible host BALB/c mice and resistant host reed vole
Yixiao Tang +8 more
doaj +1 more source
Vaccines for Human Schistosomiasis: Recent Progress, New Developments and Future Prospects
International Journal of Molecular Sciences, 2022 Schistosomiasis, caused by human trematode blood flukes (schistosomes), remains one of the most prevalent and serious of the neglected tropical parasitic diseases.
Adebayo J. Molehin, D. McManus, H. You
semanticscholar +1 more source
The Road to Elimination: Current State of Schistosomiasis Research and Progress Towards the End Game
Frontiers in Immunology, 2022 The new WHO Roadmap for Neglected Tropical Diseases targets the global elimination of schistosomiasis as a public health problem. To date, control strategies have focused on effective diagnostics, mass drug administration, complementary and integrative ...
P. Ogongo +3 more
semanticscholar +1 more source
Sja-Let-7 Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in a Mouse Model via Col1α2
Biology, 2023 Liver fibrosis (LF) is a chronic progressive disease with no definitive treatment. The aim of this study was to assess helminth-derived molecules as potential therapeutic targets to prevent or reverse LF.
Haoran Zhong +7 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2022 Preventive chemotherapy interventions for the control of soil-transmitted helminthiases (STH) and schistosomiasis scaled up from a global coverage level of around 5% in the year 2000 to a coverage that surpassed 60% in the year 2019.
A. Montresor +3 more
semanticscholar +1 more source
BMC Veterinary Research, 2021 Background N-acetyltransferase 13 (NAT13) is a probable catalytic component of the ARD1A-NARG1 complex possessing alpha (N-terminal) acetyltransferase activity.
Yalan Tang +12 more
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Elimination of Schistosomiasis Japonica in China: From the One Health Perspective
China CDC Weekly, 2022 Schistosomiasis japonica is caused by infection of Schistosoma japonicum (S. japonicum), which infected 12 million residents in the 1950s in China and was a heavy burden to public health and socioeconomic development (1). After more than seven decades of
Zhong Hong +6 more
semanticscholar +1 more source