Results 71 to 80 of about 28,464 (244)

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]

, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda, Celias, Daiana Pamela, Cervi, Laura Alejandra, Chiapello, Laura Silvina, Motran, Claudia Cristina, Silvane, Leonardo Micael, Theumer, Martín Gustavo, Volpini, Ximena   +7 more
core   +1 more source

The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira, Robson Xavier Faria, Wei Wang   +2 more
wiley   +1 more source

Development, validation, and pilot application of a high throughput molecular xenomonitoring assay to detect Schistosoma mansoni and other trematode species within Biomphalaria freshwater snail hosts

Current Research in Parasitology and Vector-Borne Diseases
Schistosomiasis is a neglected tropical disease (NTD) caused by infection with parasitic trematodes of the genus Schistosoma that can lead to debilitating morbidity and mortality.
John Archer, Shi Min Yeo, Grace Gadd, Tom Pennance, Lucas J. Cunningham, Alexandra Juhàsz, Sam Jones, Priscilla Chammudzi, Donales R. Kapira, David Lally, Gladys Namacha, Bright Mainga, Peter Makaula, James E. LaCourse, Sekeleghe A. Kayuni, Janelisa Musaya, J. Russell Stothard, Bonnie L. Webster   +17 more
doaj   +1 more source

Mouse model of Schistosomiasis: infection with Schistosoma mansoni in CD-1 mice [PDF]

, 2019
Schistosomiasis is a parasitic disease that affects almost 240 million worldwide. CD1 mice were infected with cercariae of S. mansoni, after which infection developed for 8 weeks. Tissues were processed to immuno-histological techniques.
Botelho, M., Fernandes, R., Luis, C., Soares, R.   +3 more
core  

Hidden in Plain Sight: The Enduring Challenge of Neglected Tropical Diseases in Khartoum State, Sudan

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Neglected tropical diseases (NTDs) disproportionately affect impoverished populations in tropical regions. Despite their significant health burden, data on NTD prevalence and distribution are limited in many areas, including Khartoum State, Sudan.
Babiker Mohamed Rahamtalla, Max Carlos Ramirez-Soto   +1 more
wiley   +1 more source

Pseudothrombocytopenia in schistosomiasis mansoni [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2011
We wish to communicate the case of a young patient with schistosomiasis mansoni and pseudothrombocytopenia. Failure to recognize pseudothrombocytopenia (PTCP) leads to unnecessary diagnostic tests, unnecessary therapies such as steroid administration and splenectomy, delay in treatment and unwarranted exposure to transfusion-related complications ...
Lambertucci, José Roberto, Duani, Helena, Prata, Pedro Henrique, Voieta, Izabela   +3 more
openaire   +3 more sources

Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs [PDF]

, 2009
Treatment with praziquantel (PZQ) has become virtually the sole basis of schistosomiasis control in sub-Saharan Africa and elsewhere, and the drug is reviewed here in the context of the increasing rate that it is being used for this purpose. Attention is
A. MBAYE, Alonso, Baard, Barakat, Botros, Botros, Cioli, D. CIOLI, D. ENGELS, G. COLES, Keiser, L. A. TCHUEM TCHUENTÉ, L. PICA-MATTOCCIA, M. J. DOENHOFF, Mwanakasale, N'Goran, P. HAGAN, Pica-Mattoccia, S. BOTROS, Stohler, Utzinger, V. SOUTHGATE, Van Wyk   +22 more
core   +2 more sources

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives

ChemPlusChem, Volume 90, Issue 12, December 10, 2025.
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Silvia Roscales, Aurelio G. Csáky
wiley   +1 more source

Assessment of schistosomiasis in the semi-arid Northeast region of Brazil: the São Francisco River large-scale water transposition project

Revista da Sociedade Brasileira de Medicina Tropical, 2016
: INTRODUCTION Risk of schistosomiasis expansion to semi-arid northeastern Brazil under the influence of the Integration Project of the São Francisco River (IPSFR) was assessed.
Tereza Cristina Favre, Monica Ammon Fernandez, Lilian Christina Nóbrega Holsbach Beck, Ricardo José de Paula Souza Guimarães, Otávio Sarmento Pieri, Silvana Aparecida Carvalho Thiengo   +5 more
doaj   +1 more source

Resolution of inflammation in pulmonary arterial hypertension, the influence of sex—An IUPHAR immunopharmacology committee review

British Journal of Pharmacology, Volume 182, Issue 23, Page 5706-5733, December 2025.
Pulmonary arterial hypertension (PAH) is a progressive and life‐threatening disease with limited treatment options. Sex differences are apparent in PAH, specifically in the pathophysiology, prognoses and pharmacological responses of patients. Inflammation and its resolution, which often differ between sexes, are dysregulated in chronic inflammatory ...
Chloe Landy, Miles J. De Blasio, Owen L. Woodman, Pasquale Maffia, Hong Yong Peh, Cheng Xue Qin   +5 more
wiley   +1 more source