Results 91 to 100 of about 267,561 (201)
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Criminal Behaviour and Mental Health, EarlyView.ABSTRACT Background Depression, anxiety and criminal behaviour are often correlated, but the direction and nature of these associations remain contested. Aims To investigate the temporal relationships between depression and/or anxiety and criminal behaviour at age 32 and depression and/or anxiety and criminal behaviour at age 48.
Kim Reising, Maria M. Ttofi
wiley +1 more source
Criminal Behaviour and Mental Health, EarlyView.ABSTRACT Background Prisoners experience poor mental health and well‐being in prison, including severe mental illnesses. However, access to mental health support and treatment in prison is limited. We conducted an integrative review to synthesise prisoners' experiences of living with mental ill health and/or seeking or receiving mental health support ...
Anne Kairu +5 more
wiley +1 more source
Criminal Behaviour and Mental Health, EarlyView.ABSTRACT Background Mental health courts divert individuals with serious mental illness away from imprisonment into community‐based treatment and supervision. Early research indicates that such treatment contracts can reduce recidivism and provide various other benefits. Aspects of eligibility for this diversion option are still under‐researched.
Steven Keener, Audrey Morrison
wiley +1 more source
Criminal Behaviour and Mental Health, EarlyView.ABSTRACT Background Adolescents involved in the juvenile justice system have high rates of psychiatric disorder and social vulnerability. Those in custodial or semi‐custodial detention may be particularly vulnerable to psychiatric emergencies, but the clinical factors associated with these crises remain insufficiently understood.
Maria Carolina Lobato Machado +7 more
wiley +1 more source
Power spectral density and the brain
Canadian Journal of Statistics, EarlyView.Abstract Time series from M/EEG (magneto/electroencephalography) and ECoG (electrocorticography) recordings are common sources of information about brain function. The power spectral density (PSD) preserves much of this information, up to second order. In the current decade, a burst of brain diagnostics using the slope of log(PSD) has appeared.
Priscilla E. Greenwood +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples +10 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.A mechanistic CNS PBPK model framework was applied to eight antipsychotic D2 receptor ligands, comparing brain extracellular fluid (brainECF) and brain cell membrane (brainM) as biophase for predicting human receptor occupancy compared against PET neuroimaging data. BrainM concentrations showed improved agreement with PET‐derived receptor occupancy for
Divakar Budda +2 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai +12 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective This study examined cortical thickness and appetite‐regulating hormones—neuropeptide Y (NPY) and ghrelin—to better understand the neurobiological mechanisms underlying binge eating disorder (BED) and obesity in adolescence. We compared adolescents with BED and obesity, adolescents with obesity without BED, and healthy controls (HCs),
Serkan Turan +10 more
wiley +1 more source