Results 181 to 190 of about 258,912 (200)

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

open access: yesThe Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan   +9 more
wiley   +1 more source

Predicting brain age in children aged 2–6 years with autism spectrum disorders using routine T1‐ and T2‐weighted magnetic resonance imaging

open access: yesPediatric Investigation, EarlyView.
The routine magnetic resonance imaging‐based model accurately predicted brain age in children aged 2–6. Children with autism spectrum disorder (ASD) exhibited maturational delays at ages 3–5, shifting toward accelerated aging by age 5–6. This exploratory result highlights the dynamic, age‐related developmental heterogeneity in ASD.
Zunying Hu   +7 more
wiley   +1 more source

A Schizophrenia‐Spectrum Presentation with Panda Sign: Huntington's Disease Confirmed, Wilson Disease Excluded

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Eva‐Maria Tsapakis   +5 more
wiley   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve   +6 more
wiley   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale   +4 more
wiley   +1 more source

What entrepreneurial decisions enable the breeding of digital platform unicorns?

open access: yesStrategic Entrepreneurship Journal, EarlyView.
Abstract Research Summary Digital platforms have revolutionized business sectors; however, despite their significant success, platform unicorns remain rare. While extensive research exists on digital platform growth, it is uncertain what entrepreneurial decisions achieve unicorn status.
Sea Matilda Bez   +3 more
wiley   +1 more source

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