Results 111 to 120 of about 1,069,369 (339)

Participation for mental health service development in China: Conditions, challenges, facilitators, and outcomes

American Journal of Community Psychology, EarlyView.
Abstract This study analyzes a participatory project to develop peer support services for people with serious mental illnesses (SMIs) in China. Drawing on interviews with psychiatrists, social workers, service users, and a family caregiver, it examines the conditions, challenges, facilitators, and outcomes of participation in a paternalistic context ...
Zhiying Ma, Yu Fan, Xiyuan Chen, Lindsay Sheehan, Sang Qin, Aoxuan Cao, Liang Zhou   +6 more
wiley   +1 more source

Risk and protective factors for release in outpatients with schizophrenia [PDF]

, 2015
eposterWe aim to determine risk and protective factors influencing relapse incidence in outpatient with schizophrenia. A longitudinal, observational study was done with outpatients with schizophrenia (F20) or schizoaffective disorder (F25)(DMS-IV and ...
Bellido, M Victoria, Bellido-Estevez, Inmaculada, Blanco-Reina, Encarnacion, Gómez-Luque, A., Lopez, C   +4 more
core  

Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort [PDF]

, 2018
Background: There is strong evidence that people born in winter and in spring have a small increased risk of schizophrenia. As this ‘season of birth’ effect underpins some of the most influential hypotheses concerning potentially modifiable risk ...
Escott-Price, Valentina, Kendall, Kimberley, Kirov, George, O'Donovan, Michael C., Owen, Michael J., Smith, Daniel J., Walters, James, Ward, Joey   +7 more
core   +3 more sources

Appraisal of Gene Expression‐Based Classifiers for Neuropsychiatric Disorders: A Meta‐Regression

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A substantial body of research examines the potential of gene‐expression‐based biomarkers for diagnosing and selecting treatments for neuropsychiatric disorders, yet no clear consensus has been reached regarding the influence of controllable factors such as study design and model selection on the performance of gene‐expression‐based ...
Ali Razavi, Brittany Arensman, Eric J. Barnett, Leo A. Lee, Stephen V. Faraone, Stephen J. Glatt, Jonathan L. Hess   +6 more
wiley   +1 more source

Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci. [PDF]

, 2013
Genetic and environmental components as well as their interaction contribute to the risk of schizophrenia, making it highly relevant to include environmental factors in genetic studies of schizophrenia.
A D Børglum, A Hedemand, A Ludwig, A Miyashita, A Terracciano, A Uitterlinden, AC Need, AC Ravanpay, AD Skol, AG Cardno, AR Fisher, AR Morgan, AS Brown, AS Brown, AS Yap, B Janssens, B Nørgaard-Pedersen, B Xu, BH Shirts, BJ Fredette, BM Gumbiner, BM Neale, BM Neale, C B Pedersen, C Ciatto, C Wiuf, CB Pedersen, CE Murcray, CM Nievergelt, D Demontis, D Demontis, D M Hougaard, D Moreno-De-Luca, DB Boivin, GR Abecasis, H Le-Niculescu, H Stefansson, H Stefansson, HA Mansour, HA Mansour, HC So, I Sousa, J Grove, J Lasky-Su, J Majercak, J Novembre, J Pallesen, J Shi, J van Os, J Yang, JA Embil, JE Buizer-Voskamp, JJ Kim, K Wang, K Wulff, K Zhou, KH Baratz, KP Lesch, L Athanasiu, LN Moens, M Didriksen, M M Nöthen, M Mattheisen, M Nordentoft, M Nyegaard, M Nyegaard, M Rietschel, M Rietschel, M Scholz, M Takeichi, M Takeichi, M V Hollegaard, ML Rao, MS Keshavan, MV Hollegaard, N Cermakian, N Patterson, O Mors, O Mors, P B Mortensen, PA Holmans, PB Mortensen, PF Sullivan, R A Ophoff, R H Yolken, R Steinberg, RL Schelonka, S Cichon, S Purcell, S Ripke, S Steinberg, SA Riazuddin, SA Staras, SH Lee, SJ Sanders, SL Buka, SL Buka, SM Purcell, T Miyoshi, T Takeuchi, T Ørntoft, TJ Crow, TL Edwards, V Busby, V Soria, VR Sobrado, X Liang, Y Adachi, Y Li   +108 more
core   +4 more sources

Rare coding variants in ten genes confer substantial risk for schizophrenia

Nature, 2022
T. Singh, T. Poterba, D. Curtis, H. Akil, M. A. Al Eissa, J. Barchas, N. Bass, T. Bigdeli, G. Breen, E. Bromet, Peter F. Buckley, W. Bunney, J. Bybjerg-Grauholm, W. Byerley, S. Chapman, Wei J. Chen, C. Churchhouse, N. Craddock, C. Cusick, L. DeLisi, S. Dodge, M. Escamilla, S. Eskelinen, A. Fanous, S. Faraone, A. Fiorentino, L. Francioli, S. Gabriel, D. Gage, S. G. Gagliano Taliun, A. Ganna, G. Genovese, D. Glahn, J. Grove, M. Hall, E. Hämäläinen, H. Heyne, M. Holi, D. Hougaard, D. Howrigan, Hailiang Huang, H. Hwu, R. Kahn, H. Kang, K. Karczewski, G. Kirov, J. Knowles, F. Lee, D. Lehrer, F. Lescai, D. Malaspina, S. Marder, S. Mccarroll, A. McIntosh, H. Medeiros, L. Milani, C. Morley, D. Morris, P. Mortensen, R. Myers, M. Nordentoft, N. O’Brien, A. M. Olivares, D. Ongur, W. Ouwehand, D. Palmer, T. Paunio, D. Quested, M. Rapaport, E. Rees, B. Rollins, F. Satterstrom, A. Schatzberg, E. Scolnick, L. Scott, Sally Sharp, P. Sklar, J. Smoller, J. Sobell, M. Solomonson, E. Stahl, C. Stevens, J. Suvisaari, G. Tiao, S. Watson, N. Watts, D. Blackwood, A. Børglum, B. Cohen, A. Corvin, T. Esko, N. Freimer, S. Glatt, C. Hultman, A. McQuillin, A. Palotie, C. Pato, M. Pato, A. Pulver, D. St. Clair, M. Tsuang, M. Vawter, J. Walters, T. Werge, R. Ophoff, Patrick F. Sullivan, M. Owen, M. Boehnke, M. O’Donovan, B. Neale, M. Daly   +110 more
semanticscholar   +1 more source

Rüdin's Unpublished Family Study From the Early 1920s: “On the Inheritance of Manic‐Depressive Insanity”

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Ernst Rüdin, an important and controversial figure in the history of psychiatric genetics, published only one major empirical study on siblings of dementia praecox (DP) probands in 1916. He conducted a parallel study of siblings of probands with manic‐depressive insanity (MDI), but the resulting monograph, written in the early 1920s, was left ...
Kenneth S. Kendler, Astrid Klee
wiley   +1 more source

Schizophrenia Genetics Modulates Clinical Depressive Features

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti, Daniel Souery, Siegfried Kasper, Joseph Zohar, Stuart Montgomery, Panagiotis Ferentinos, Dan Rujescu, Raffaele Ferri, Giuseppe Fanelli, Chiara Fabbri, Raffaella Zanardi, Francesco Benedetti, Bernhard T. Baune, Julien Mendlewicz   +13 more
wiley   +1 more source

Metabotropic glutamate 2/3 receptors and epigenetic modifications in psychotic disorders: a review [PDF]

, 2016
Schizophrenia and Bipolar Disorder are chronic psychiatric disorders, both considered as "major psychosis"; they are thought to share some pathogenetic factors involving a dysfunctional gene x environment interaction.
Grayson, Danis R, Guidotti, Alessandro, MATRISCIANO, FRANCESCO, NICOLETTI, Ferdinando, PANACCIONE, ISABELLA   +4 more
core   +2 more sources

Descriptive Epidemiology From the Myhre Syndrome Foundation Registry: The Value of Self‐Reported Data

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young, Armelle Pindon, Maggie R. Brand, Kate Wears, Katherine H. Young, Alyssa Mendel, Michael J. Lyons   +6 more
wiley   +1 more source