Results 111 to 120 of about 598,095 (375)

Reward Processing as an Indicator of Vulnerability or Compensatory Resilience in Psychoses? Results From a Twin Study

open access: yesBiological Psychiatry Global Open Science, 2023
Background: Findings of reward disturbances in unaffected relatives of patients with schizophrenia suggest reward disturbances as an endophenotype for schizophrenia.
Mette Ødegaard Nielsen   +8 more
doaj  

Natural History of NAA15‐Related Neurodevelopmental Disorder Through Adolescence

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The NatA N‐terminal acetyltransferase complex is composed of the NAA10 catalytic subunit and the auxiliary subunits NAA15 and HYPK. While those with variants in the enzymatic subunit develop Ogden Syndrome, individuals with variants in the NAA15 coding region develop NAA15‐related neurodevelopmental syndrome, which presents with a wide array ...
Rikhil Makwana   +5 more
wiley   +1 more source

Real‐time assessment of positive and negative affective fluctuations and mood lability in a transdiagnostic sample of youth

open access: yesDepression and Anxiety, Volume 39, Issue 12, Page 870-880, December 2022., 2022
Abstract Background Emotional lability, defined as rapid and/or intense affect fluctuations, is associated with pediatric psychopathology. Although numerous studies have examined labile mood in clinical groups, few studies have used real‐time assessments in a well‐characterized transdiagnostic sample, and no prior study has included participants with ...
Reut Naim   +5 more
wiley   +1 more source

Beyond the Extra X and Y Chromosome: The Contribution of Familial Risk for Psychopathology to the Neurodevelopmental Phenotype of Children With Sex Chromosome Trisomy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Individuals with an extra X or Y chromosome (sex chromosome trisomy or SCT) have an increased risk for symptoms of psychopathology and neurocognitive dysfunction. In this study, we evaluated the contribution of family history (FH) of neuropsychiatric or neurocognitive disorders to the phenotype of SCT. One hundred and six children with SCT and
Sophie van Rijn   +2 more
wiley   +1 more source

What does a mouse tell us about neuregulin 1 – cannabis interactions?

open access: yesFrontiers in Cellular Neuroscience, 2013
The link between cannabis and psychosis has been debated although there is substantial epidemiological evidence showing that cannabis increases the risk of psychosis.
Tim eKarl   +5 more
doaj   +1 more source

Global economic burden of schizophrenia: a systematic review

open access: yesNeuropsychiatric Disease and Treatment, 2016
Background Schizophrenia is one of the top 25 leading causes of disability worldwide in 2013. Despite its low prevalence, its health, social, and economic burden has been tremendous, not only for patients but also for families, caregivers, and the wider ...
H. Chong   +5 more
semanticscholar   +1 more source

What is schizophrenia?

open access: yesSchizophrenia bulletin, 2019
Many who pick up this book will be learning about schizophrenia for the first time, either because someone they care about has recently been diagnosed, or purely out of academic interest.
J. S. Strauss   +3 more
semanticscholar   +1 more source

Association Between Polygenic Risk and Symptom Severity Change After Cognitive Behavioral Therapy for Obsessive‐Compulsive Disorder

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A large proportion of patients undergoing cognitive behavior therapy (CBT) for obsessive‐compulsive disorder (OCD) do not respond sufficiently to treatment. Identifying predictors for change in symptom severity after treatment could inform clinical decision‐making, allow for better‐tailored interventions, and avoid treatment failure.
Julia Bäckman   +39 more
wiley   +1 more source

Correction to: Skating on thin ice: pragmatic prescribing for medication refractory schizophrenia

open access: yesBMC Psychiatry, 2019
After publication of the original article [1], the authors have notified us that there was an oversight on acknowledging funding received for the study. They would like to mention that Professor Sukhi Shergill was funded by an ERC Consolidator Award.
Derek K. Tracy   +4 more
doaj   +1 more source

A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time?

open access: yesArchives of General Psychiatry, 2007
CONTEXT Despite improvements in mental health services in recent decades, it is unclear whether the risk of mortality in schizophrenia has changed over time.
S. Saha, D. Chant, J. Mcgrath
semanticscholar   +1 more source

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