Results 111 to 120 of about 620,945 (334)

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

THE EFFORT TO DRIVE THE OTHER PERSON CRAZY—AN ELEMENT IN THE AETIOLOGY AND PSYCHOTHERAPY OF SCHIZOPHRENIA [PDF]

, 1959
Harold F. Searles
openalex   +1 more source

Associations Between Nicotine Metabolites and Serum Neurofilament Light Chain Levels in the General Population

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Background Nicotine has been associated with cognitive functions such as memory and attention, with serum neurofilament light chain (sNfL) as a biomarker for neurological diseases such as Alzheimer's disease (AD) and multiple sclerosis (MS).
Qianqian Ji, Erhan Tang, Yueting Liao, Jialei Yang, Yunzhang Wang, Yiqiang Zhan   +5 more
wiley   +1 more source

THE EPILEPTIC THRESHOLD IN SCHIZOPHRENIA [PDF]

, 1953
John M. Hoenig, D. M. Leiberman
openalex   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs as Modulators of Cation Channels: Fenamates Repurposing in Channelopathies

ChemMedChem, EarlyView.
Beyond their established role as nonsteroidal anti‐inflammatory drugs (NSAIDs), fenamates (niflumic, flufenamic, mefenamic, meclofenamic, and tolfenamic acids) have recently been identified as modulators of cationic ion channels. This review highlights their differential effects on ion channel activity and explores their potential for repurposing in ...
Paola Laghetti, Concetta Altamura, Simone Dell’Atti, Jean‐François Desaphy, Ilaria Saltarella   +4 more
wiley   +1 more source

Cardiazol Convulsion Therapy in Schizophrenia [PDF]

, 1938
L. C. Cook
openalex   +1 more source

Exposure–Response Analysis for Aripiprazole Once‐Monthly in Patients Diagnosed With Bipolar I Disorder

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Aripiprazole once‐monthly (AOM) is approved for the maintenance monotherapy treatment of bipolar I disorder (BP‐I) in adults. A previously developed population pharmacokinetic model was validated by applying it to data from patients diagnosed with BP‐I.
Xiaofeng Wang, Luann Phillips, Matthew Harlin, Karimah S. Bell Lynum, Frank Larsen, Pedro Such, Jessica Madera‐McDonough, Murat Yildirim, Ric M. Procyshyn, Craig Chepke, Julie Passarell   +10 more
wiley   +1 more source

Exploring the feasibility and acceptability of DIALOG+ (a structured digital communication tool) in strengthening psychiatric care in India and Pakistan: a qualitative pilot study

BMJ Open
Objectives To assess the implementation feasibility and acceptability of a structured digital psychosocial communication tool (DIALOG+) to strengthen the quality of person-centric care in psychiatric settings within Pakistan and India.Design A hybrid ...
Sana Zehra Sajun, Victoria Jane Bird, Lakshmi Venkatraman, Padmavati Ramachandran, Aneeta Pasha, Renata Peppl, Onaiza Qureshi, Krishna Priya, Hufsa Sarwar, Kasthuri Divya, Mehwish Dawood, Syjo Davis, Maria Baig, Manikandan Pari, Areeba Shahab   +14 more
doaj   +1 more source

Prognosis in schizophrenia; A study of 271 cases [PDF]

, 1941
Daniel Silverman
openalex   +1 more source

Pleiotropy and the Increasing Complexity of Parkinson's Disease Genetics

Annals of Neurology, EarlyView.
Jonggeol Kim, Joshua M. Shulman
wiley   +1 more source