Results 91 to 100 of about 200,189 (245)

Extending the ATP9A‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this gene was identified as being associated with a recessive neurodevelopmental ...
Camille Verebi, Céline Louveau, Bertrand Diebold, Natacha Gaitch, Arnaud Hubas, Martine Gautier Vallee, Jérôme Champ, Anais L'Haridon, Sophie Georgin Lavialle, Boris Chaumette, Thierry Bienvenu   +10 more
wiley   +1 more source

Emotional intelligence in schizophrenia [PDF]

, 2008
Deficits in emotion perception have been extensively documented in schizophrenia and are associated with poor psychosocial functioning. However, little is known about other aspects of emotion processing that are critical for adaptive functioning.
Robert S. Kern, William P. Horan, Peter Salovey, Kenneth L. Subotnik, Catherine A. Sugar, Kimmy S. Kee, Mark J. Sergi, Keith Nuechterlein, Junghee Lee, Alan P. Fiske, Michael F. Green   +10 more
core  

The diagnostic value of the circadian rhythm gene KLF10 in anxiety‐depressive disorders and its neuroimmune regulatory mechanisms

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the protective role and molecular mechanism of the circadian rhythm‐related gene KLF10, identified as a diagnostic biomarker and therapeutic target in anxiety‐depressive disorder. Model establishment and phenotypes: An anxiety‐depression model was successfully established by chronic restraint stress combined with ...
Anlan Liu, Weifeng Guo, Jianxiang Li, Tiange Zhang, Dan Xu   +4 more
wiley   +1 more source

The MR neuroimaging protocol for the Accelerating Medicines Partnership® Schizophrenia Program.

Neuroimaging with MRI has been a frequent component of studies of individuals at clinical high risk (CHR) for developing psychosis, with goals of understanding potential brain regions and systems impacted in the CHR state and identifying prognostic or ...
Yassin, W., Hui, CLM, Kambeitz-Ilankovic, L., Schiffman, J., Kane, J.M., Rogers, J., Bolo, N.R., Smesny, S., Choi, J., Wang, J., Sabb, F.W., Diaz-Caneja, C.M., Laulette, K., Wood, S.J., Gaspar, P.A., Chen, EYH, Stone, W.S., Lindberg, U., Poldrack, R.A., Kubicki, M., Kahn, R.S., Kwon, J.S., Alameda, L., Goncalves, M., Shah, J.L., Kotler, E., Verma, S.K., Wannan, C., Nordentoft, M., Cadenhead, K.S., Cornblatt, B.A., Bearden, C.E., Campbell, D., Koutsouleris, N., Cecchi, G., Arango, C., Mittal, V.A., Langbein, K., Mamah, D., Romo, P.A., Corcoran, C.M., Cannon, T.D., Kapur, T., Horton, L.E., Nelson, B., Zhou, J.H., Strauss, G.P., McGorry, P.D., Rathi, Y., Mathalon, D.H., Calkins, M.E., Shenton, M.E., Markiewicz, C., Ning, L., Anticevic, A., Harms, M.P., Bouix, S., Keshavan, M.S., John, O., Conus, P., Thompson, J.L., Kuperman, J.M., Broome, M.R., Kambeitz, J., Gerber, C., Wolf, D.H., Silverstein, S.M., Haidar, A., Breitborde, NJK, Perez, J., Tamayo, Z., Woods, S.W., Powers, A.R., Hughes, D.E., Wickham, A., Addington, J., Perkins, D.O., Upthegrove, R., Cho, K.K., Kim, N., Fusar-Poli, P., Kim, S.W., Izyurov, I., Ellman, L.M., Glenthøj, L.B., Pasternak, O., Pearlson, G.D.   +86 more
core   +1 more source

Emotional Prosody Processing in the Schizophrenia Spectrum. [PDF]

, 2011
THESIS ABSTRACT Emotional prosody processing impairment is proposed to be a main contributing factor for the formation of auditory verbal hallucinations in patients with schizophrenia.
ALBA-FERRARA, LUCIA,MONSERRAT
core  

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

Annals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl, We Fong Siah, Jasmin Lope, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Alison Toomey, Jana Kleinerova, Peter Bede   +10 more
wiley   +1 more source

Lipidomics Reveals Early Metabolic Changes in Subjects with Schizophrenia: Effects of Atypical Antipsychotics [PDF]

, 2013
There is a critical need for mapping early metabolic changes in schizophrenia to capture failures in regulation of biochemical pathways and networks.
Buckley, P, Kaddurah-Daouk, Rima, George G. Dougherty (436720), Peter Buckley (436718), Nasrallah Henry A., Joseph McEvoy, Baillie Rebecca A., Yao Jeffrey K., Nasrallah, HA, Zhu, H, Nasrallah, Henry A., Dougherty, GG, Zhu, Hongjie, Keshavan, Matcheri, Kaddurah-Daouk Rima, Peter Buckley, Keshavan, Matcheri S., Keshavan Matcheri S., Matcheri S Keshavan, Keshavan, MS, George G Dougherty, McEvoy, J, Hongjie Zhu (152174), Dougherty, George G., Henry A Nasrallah, Matcheri S. Keshavan (311472), Rima Kaddurah-Daouk (152187), Buckley Peter, Baillie, RA, McEvoy, Joseph, Hongjie Zhu, Rima Kaddurah-Daouk, McEvoy Joseph, Henry A. Nasrallah (436719), Yao, Jeffrey K., Joseph McEvoy (311475), Buckley, Peter, Kaddurah-Daouk, R, Rebecca A Baillie, Rebecca A. Baillie (152180), Dougherty George G., Jeffrey K Yao, Baillie, Rebecca A., Jeffrey K. Yao (311469), Yao, JK, Zhu Hongjie   +45 more
core   +2 more sources

Cortical Thickness and White Matter Surface Morphology in Tourette Syndrome: A Cohort Study

Annals of Neurology, EarlyView.
Objective To examine cortical thickness and white matter surface morphology in a large sample of individuals with Tourette syndrome (TS) and neurotypical controls across the lifespan, and to assess associations with symptom severity, comorbidities, and medication use.
Sahar Delavari, Adam C. Frank, Ravi Bansal, Flora M. Vaccarino, Robert A. King, Paul Lombroso, Lawrence Scahill, James F. Leckman, Bradley S. Peterson   +8 more
wiley   +1 more source

Cognition impairment in schizophrenia patients with tardive dyskinesia: Association with plasma superoxide dismutase activity

, 2014
Long-term antipsychotic treatment for schizophrenia is often associated with the emergence of tardive dyskinesia (TD), and TD presence is also accompanied by more severe cognitive impairment.
Tan, Yun Long, Wu, Jing Qin, Chen, Da Chun, Zhang, Xiang Yang, Yang, Fu De, Xiu, Mei Hong, Tan, Shu Ping, Wang, Zhi Ren   +7 more
core   +1 more source

Hyperostosis frontalis interna: Observed patterns, prevalence, and dementia associations in older adults

The Anatomical Record, EarlyView.
Abstract Hyperostosis frontalis interna (HFI) is a frequently underrecognized condition characterized by overgrowth of the frontal endocranium, most commonly observed in post‐menopausal women. Although its etiology remains unclear, hormonal influences and a possible relationship with neurocognitive changes have been proposed.
Danielle Felsberg, Kira Morgan, Rickey‐Levon Burch, Madelyn Furr, Zachary Tyson, Steven Lesh   +5 more
wiley   +1 more source