Results 81 to 90 of about 200,189 (245)

Estrogens and gonadal function in schizophrenia and related psychoses [PDF]

, 2011
Recent research has increasingly pointed to the importance of estrogens and the hypothalamic-pituitary-gonadal axis in schizophrenia. Specifically, there is mounting evidence from clinical, epidemiological, and basic research that estradiol, the main ...
Riecher-Rössler, Anita, Kulkarni, Jayashri   +1 more
core  

Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri, Alessandro Serretti, Marco Menchetti, Benedetta Vai, Francesco Benedetti, Lidia Fortaner‐Uyà, Concetta Crisafulli   +6 more
wiley   +1 more source

The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle, Silvia Iñiguez‐Barrio, Maria Aurora Arrue, Leire Erkoreka   +3 more
wiley   +1 more source

Still Regarding Schizophrenia, Secondary Schizophrenia, Pseudo-Schizophrenia, and Schizophrenia-Like Psychosis

Acta Médica Portuguesa, 2022
N/a.
openaire   +3 more sources

Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring [PDF]

, 2009
Over the last 2 decades, a large number of neurophysiological and neuroimaging studies of patients with schizophrenia have furnished in vivo evidence for dysconnectivity, ie, abnormal functional integration of brain processes.
Friston, K J, Frith, C D, Frith, C. D., Stephan, K E, Stephan, K. E., Friston, K. J.   +5 more
core   +1 more source

Genetic Variants of Na+,K+‐ATPase Associated With Neurological Disorders: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Neurological disorders encompass a wide range of severe symptoms and manifestations, many of which are associated with genetic variants that affect ionic homeostasis. Na+,K+‐ATPase, a transmembrane enzyme responsible for maintaining electrochemical gradients in cells, plays a crucial role in neuronal excitability and brain function.
Giovana Kummer da Rosa, Leandro Rodrigo Ribeiro, Jéssica Lorena Bariviera, Mauro Schneider Oliveira   +3 more
wiley   +1 more source

Sample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program

Clinical ascertainment and clinical outcome are key features of any large multisite study. In the ProNET and PRESCIENT research networks, the Accelerating Medicines Partnership® Schizophrenia (AMP®SCZ) Clinical Ascertainment and Outcome Measures Team ...
Schiffman, J, Kambeitz-Ilankovic, L., Schiffman, J., Kane, J.M., Koutsouleris, N, Smesny, S., Cornblatt, BA, Walsh, BC, Wang, J., Dwyer, D, Diaz-Caneja, C.M., Silverstein, SM, Mittal, VA, Strauss, GP, Kahn, R.S., Kwon, J.S., Kwon, JS, Upthegrove, R, Perez, J, Shah, J.L., Nordentoft, M., Cadenhead, K.S., Mourgues-Codern, C.V., Bearden, C.E., Koutsouleris, N., Cadenhead, KS, Arango, C., Braun, A., Wolf, DH, Alameda, LK, Nordentoft, M, Mathalon, DH, Verma, S., Penzel, N, Liu, L., Horton, L.E., Nelson, B., Wastler, H.M., Jacobs, GR, Auther, A., Horton, LE, Liu, L, Mamah, D, Corcoran, CM, Wang, J, Walsh, B.C., Bouix, S., Conus, P., Rogers, J, Thompson, J.L., Auther, A, Broome, M.R., Kambeitz, J., Gerber, C., Smesny, S, Wolf, D.H., Carrion, R.E., Silverstein, S.M., Kane, JM, Coleman, M.J., Nelson, B, Stone, WS, Oliver, D, Powers, A.R., Ellman, LM, Addington, J., Upthegrove, R., Wickham, A., Lewandowski, K.E., Lewandowski, KE, Fusar-Poli, P., Kim, S.W., Buccilli, K., Ellman, L.M., Glenthøj, L.B., Braun, A, Kahn, RS, Sabb, FW, Bearden, CE, Broome, MR, Jacobs, G.R., Rogers, J., Verma, S, Perkins, DO, Thompson, A, Choi, J., Rossum, IWV, Hui, C, Sabb, F.W., Faghankhani, M, Nunez, A.R., Gaspar, P.A., Chen, EYH, Stone, W.S., Arango, C, Keshavan, MS, Gaspar, PA, Pasternak, O, Bouix, S, Cornblatt, B.A., Kim, SW, Rossum, I.W., Alameda, L.K., Mittal, V.A., Marcy, PJ, McGorry, PD, Langbein, K., Yung, A.R., Mamah, D., Corcoran, C.M., Thompson, A., Conus, P, Powers, AR, Gerber, C, Oliver, D., Wickham, A, Kambeitz, J, Strauss, G.P., McGorry, P.D., Faghankhani, M., Mourgues-Codern, CV, Mathalon, D.H., Calkins, M.E., Shenton, M.E., Shah, JL, Wastler, HM, Marcy, P.J., Penzel, N., Choi, J, Langbein, K, Kambeitz-Ilankovic, L, Nunez, AR, Diaz-Caneja, CM, Hui, C., Carrion, RE, Keshavan, M.S., Woods, SW, Shenton, ME, Coleman, MJ, Kerr, M.J., Thompson, JL, Fusar-Poli, P, Calkins, ME, Buccilli, K, Yung, AR, Breitborde, NJK, Dwyer, D., Perez, J., Glenthøj, LB, Woods, S.W., Addington, J, Perkins, D.O., Pasternak, O., Kerr, MJ, Pearlson, G.D., Pearlson, GD   +155 more
core   +1 more source

What is the best approach to treating schizophrenia in developing countries? [PDF]

, 2007
Schizophrenia affects an estimated 25 million people in low- and middle-income countries, with an average lifetime risk of about 1%. The illness is associated with excess mortality from a variety of causes.
Vikram Patel, Thara R, Saeed Farooq, R Thara, Patel, Vikram, Thara, R, Farooq, Saeed, Farooq Saeed, Patel Vikram   +8 more
core   +1 more source

What drives prolonged hospital stays in schizophrenia‐spectrum disorders? A Canadian tertiary care review

PCN Reports
Aim Schizophrenia imposes significant economic and social burdens, often resulting in prolonged inpatient length of stay (LOS), particularly for treatment‐resistant cases.
Naista Zhand, Ali Manghi, Fatima Iftikhar, Yiling Zhu, Rebecca Sunderland, Carrie Robertson   +5 more
doaj   +1 more source

Peripheral Lipid Signatures, Metabolic Dysfunction, and Pathophysiology in Schizophrenia Spectrum Disorders

Metabolites
Metabolic dysfunction is commonly observed in schizophrenia spectrum disorders (SSDs). The causes of metabolic comorbidity in SSDs are complex and include intrinsic or biological factors linked to the disorder, which are compounded by antipsychotic (AP ...
Sally Wu, Kristoffer J. Panganiban, Jiwon Lee, Dan Li, Emily C.C. Smith, Kateryna Maksyutynska, Bailey Humber, Tariq Ahmed, Sri Mahavir Agarwal, Kristen Ward, Margaret Hahn   +10 more
doaj   +1 more source