Results 61 to 70 of about 200,189 (245)

Cannabis and schizophrenia [PDF]

Cochrane Database of Systematic Reviews, 2014
Schizophrenia is a mental illness causing disordered beliefs, ideas and sensations. Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear what the best method is to allow people with schizophrenia to alter their cannabis intake.To assess the effects
Jonathan A, Pushpa-Rajah, Benjamin C, McLoughlin, Donna, Gillies, John, Rathbone, Hannele, Variend, Eliana, Kalakouti, Katerina, Kyprianou   +6 more
openaire   +4 more sources

Carbonyl Stress and Microinflammation-Related Molecules as Potential Biomarkers in Schizophrenia

Frontiers in Psychiatry, 2018
This literature review primarily aims to summarize our research, comprising both cross-sectional and longitudinal studies, and discuss the possibility of using microinflammation-related biomarkers as peripheral biomarkers in the diagnosis and monitoring ...
Tohru Ohnuma, Shohei Nishimon, Mayu Takeda, Takahiro Sannohe, Narimasa Katsuta, Heii Arai   +5 more
doaj   +1 more source

Association Between SIRT1, Cytokines, and Metabolic Syndrome in Schizophrenia Patients With Olanzapine or Clozapine Monotherapy

Frontiers in Psychiatry, 2020
Objective: Previous studies consistently showed the interaction between Sirtuin 1 (SIRT1) and immune inflammation is significantly related to metabolic abnormalities, but their role in the pathogenesis of metabolic syndrome caused by second-generation ...
Xinyu Fang, Xinyu Fang, Lingfang Yu, Dandan Wang, Yan Chen, Yewei Wang, Zenan Wu, Ruimei Liu, Juanjuan Ren, Wei Tang, Chen Zhang   +10 more
doaj   +1 more source

Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment

Translational Psychiatry, 2021
We have reported that a subpopulation of patients with schizophrenia have lower levels of vitamin B6 (VB6) in peripheral blood than do healthy controls. In a previous study, we found that VB6 level was inversely proportional to the patient’s positive and
Kazuya Toriumi, Mitsuhiro Miyashita, Kazuhiro Suzuki, Nao Yamasaki, Misako Yasumura, Yasue Horiuchi, Akane Yoshikawa, Mai Asakura, Noriyoshi Usui, Masanari Itokawa, Makoto Arai   +10 more
doaj   +1 more source

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee, Gayeon Kim, Ellison R. Black, Seonil Kim   +3 more
wiley   +1 more source

A Language‐Guided Multimodal Foundation Model for Zero‐Shot and Multi‐Task Brain Signal Analysis

Advanced Intelligent Systems, EarlyView.
METIS aligns brain signals with natural‐language instructions to enable zero‐shot and multi‐task brain signal analysis. Pretrained on over 70 000 h of EEG and iEEG recordings, it generalizes across sleep stage classification, epilepsy detection, and neurological disorder diagnosis, providing a scalable foundation model for clinically meaningful brain ...
Mingzhi Chen, Yiyu Gui, Guibo Luo, Yuchao Yang   +3 more
wiley   +1 more source

Epidural auditory event-related potentials in the rat to frequency and duration deviants: evidence of mismatch negativity?

Frontiers in Psychology, 2011
The capacity of the human brain to detect deviance in the acoustic environment pre-attentively is reflected in a brain event-related potential (ERP), mismatch negativity (MMN).
Tamo eNakamura, Tamo eNakamura, Tamo eNakamura, Tamo eNakamura, Patricia T Michie, Patricia T Michie, Patricia T Michie, Patricia T Michie, William R Fulham, William R Fulham, William R Fulham, William R Fulham, Juanita eTodd, Juanita eTodd, Juanita eTodd, Juanita eTodd, Timothy W Budd, Timothy W Budd, Timothy W Budd, Timothy W Budd, Ulrich eSchall, Ulrich eSchall, Ulrich eSchall, Ulrich eSchall, Michael eHunter, Michael eHunter, Deborah M Hodgson, Deborah M Hodgson, Deborah M Hodgson, Deborah M Hodgson   +29 more
doaj   +1 more source

Sleep Disturbances in Adults With Tuberous Sclerosis Complex: Influences of Treatment and Clinical Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Tuberous sclerosis complex (TSC) is a genetic condition with multisystem neurocutaneous signs, including hamartomas, epilepsy, and neuropsychological difficulties. Although sleep disorders are increasingly recognized in TSC, they remain poorly described in adults.
Kirstin A. Risgaard, Laura Farach, Hope Northrup, Sarah L. Wilson, Deborah Pearson, Syed Hashmi, Kate Richardson   +6 more
wiley   +1 more source

Primary and secondary alterations of white matter connectivity in schizophrenia: A study on first-episode and chronic patients using whole-brain tractography-based analysis

, 2017
Schizophrenia is a debilitating mental disorder that is associated with an impaired connection of cerebral white matter. Studies on patients with chronic and first-episode schizophrenia have found widespread white matter abnormalities.
曾文毅;陳中明;謝明憲;黃宗正;簡意玲;劉智民;劉震鐘;胡海國, Wu, Chen-Hao;Hwang, Tzung-Jeng;Chen, Yu-Jen;Hsu, Yung-Chin;Lo, Yu-Chun;Liu, Chih-Min;Hwu, Hai-Gwo;Liu, Chen-Chung;Hsieh, Ming H.;Chien, Yi-Ling;Chen, Chung-Ming;Tseng, Wen-Yih Isaac   +1 more
core   +1 more source

Collaborative community based care for people and their families living with schizophrenia in India: protocol for a randomised controlled trial. [PDF]

, 2011
BACKGROUND: There is a large treatment gap with few community services for people with schizophrenia in low income countries largely due to the shortage of specialist mental healthcare human resources.
Thornicroft, G, Balaji, M, Leese, Morven, Varghese Mathew, Koschorke, Mirja, Sudipto Chatterjee, Mathew Varghese, McCrone, P, Rangaswamy Thara, COmmunity care for People with Schizophrenia in India (COPSI) gr, Balaji Madhumitha, Morven Leese, Hamid Dabholkar, Paul McCrone, Chatterjee, S, Dabholkar, H, John, Sujit, Koschorke Mirja, Goldsmith Kimberley, John Sujit, Chatterjee, Sudipto, Naik, S, Naik, Smita, ?, ?, Mirja Koschorke, Thara, Rangaswamy, Thornicroft Graham, null null, Varghese, M, John, S, Koschorke, M, Goldsmith, Kimberley, Vikram Patel, Dabholkar, Hamid, Sujit John, McCrone Paul, Thara, R, Balaji, Madhumitha, Kimberley Goldsmith, Leese, M, Leese Morven, Goldsmith, Kimberley; id_orcid, Thornicroft, Graham, Graham Thornicroft, Chatterjee Sudipto, Thara Rangaswamy, Goldsmith, K, Madhumitha Balaji, Patel Vikram, Varghese, Mathew, Patel, Vikram, Naik Smita, Patel, V, McCrone, Paul, Smita Naik, Dabholkar Hamid   +55 more
core   +2 more sources