Results 51 to 60 of about 389,571 (303)

Early use of electroconvulsive therapy in individuals with first episode psychosis: A case series

Indian Journal of Mental Health and Neurosciences, 2019
Array
Antra Chandan, Vijaya Raghavan
doaj   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Association Between SIRT1, Cytokines, and Metabolic Syndrome in Schizophrenia Patients With Olanzapine or Clozapine Monotherapy

Frontiers in Psychiatry, 2020
Objective: Previous studies consistently showed the interaction between Sirtuin 1 (SIRT1) and immune inflammation is significantly related to metabolic abnormalities, but their role in the pathogenesis of metabolic syndrome caused by second-generation ...
Xinyu Fang, Xinyu Fang, Lingfang Yu, Dandan Wang, Yan Chen, Yewei Wang, Zenan Wu, Ruimei Liu, Juanjuan Ren, Wei Tang, Chen Zhang   +10 more
doaj   +1 more source

Prior Expectations Bias Confidence Judgments Through Parietal Alpha‐Band Modulation

Advanced Science, EarlyView.
ABSTRACT Humans possess the metacognitive ability to estimate the likely accuracy of their own decisions through confidence judgments. Yet, whether prior information shapes confidence and the neural mechanisms mediating such influence, remain to be determined.
Luca Tarasi, Anna Pasini, Domenico Romanazzi, Margherita Covelli, Vincenzo Romei   +4 more
wiley   +1 more source

The impact of schizophrenia and intelligence on the relationship between age and brain volume

Schizophrenia Research: Cognition, 2019
Age has been shown to have an impact on both grey (GM) and white matter (WM) volume, with a steeper slope of age-related decline in schizophrenia compared to healthy controls.
Maria H. Jensen, Nikolaj Bak, Egill Rostrup, Mette Ø. Nielsen, Christos Pantelis, Birte Y. Glenthøj, Bjørn H. Ebdrup, Birgitte Fagerlund   +7 more
doaj   +1 more source

What is the best approach to treating schizophrenia in developing countries? [PDF]

, 2007
Schizophrenia affects an estimated 25 million people in low- and middle-income countries, with an average lifetime risk of about 1%. The illness is associated with excess mortality from a variety of causes.
Vikram Patel, Thara R, Saeed Farooq, R Thara, Patel, Vikram, Thara, R, Farooq, Saeed, Farooq Saeed, Patel Vikram   +8 more
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Carbonyl Stress and Microinflammation-Related Molecules as Potential Biomarkers in Schizophrenia

Frontiers in Psychiatry, 2018
This literature review primarily aims to summarize our research, comprising both cross-sectional and longitudinal studies, and discuss the possibility of using microinflammation-related biomarkers as peripheral biomarkers in the diagnosis and monitoring ...
Tohru Ohnuma, Shohei Nishimon, Mayu Takeda, Takahiro Sannohe, Narimasa Katsuta, Heii Arai   +5 more
doaj   +1 more source

On the descriptive validity of ICD-10 schizophrenia: Empirical analyses in the spectrum of non-affective functional psychoses [PDF]

, 2003
In order to examine the descriptive validity of ICD-10 schizophrenia, 1,476 consecutively admitted in-patients were included in the present study. ICD-10 schizophrenia (n = 951) was compared with other non-affective psychotic disorders {[}persistent ...
Jäger, Markus, Bottlender, Ronald, Strauss, Anton, Möller, Hans-Jürgen   +3 more
core   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source