Results 11 to 20 of about 687,888 (183)
The Lancet, 2016 Schizophrenia is a complex, heterogeneous behavioural and cognitive syndrome that seems to originate from disruption of brain development caused by genetic or environmental factors, or both. Dysfunction of dopaminergic neurotransmission contributes to the genesis of psychotic symptoms, but evidence also points to a widespread and variable involvement ...
Michael J Owen +2 more
openaire +8 more sources
Nature Reviews Disease Primers, 2015 Schizophrenia is a chronic psychiatric disorder with a heterogeneous genetic and neurobiological background that influences early brain development, and is expressed as a combination of psychotic symptoms - such as hallucinations, delusions and disorganization - and motivational and cognitive dysfunctions.
Kahn, René S. +10 more
openaire +5 more sources
The Lancet, 2022 Schizophrenia, characterised by psychotic symptoms and in many cases social and occupational decline, remains an aetiological and therapeutic challenge. Contrary to popular belief, the disorder is modestly more common in men than in women. Nor is the outcome uniformly poor.
Jauhar, Sameer +2 more
openaire +3 more sources
New England Journal of Medicine, 2020 The lifetime prevalence of schizophrenia is 1%. Schizophrenia is among the most severe mental illnesses and gives rise to the highest treatment costs per patient of any disease. It is characterized by frequent relapses, marked impairment of quality of life, and reduced social and work participation.The group entrusted with the creation of the German ...
Matthew L, Goldman +2 more
openaire +6 more sources
Búsqueda De Nuevos Biomarcadores De La Cognición En Esquizofrenia
Schizophrenia Research: Cognition, 2015 La búsqueda de biomarcadores en la cognición ha centrado una gran parte de las investigaciones en pacientes con esquizofrenia. La literatura científica es heterogénea y son escasos los estudios disponibles que permitan establecer un modelo integrador de ...
Rafael Penadés +6 more
doaj +1 more source
Increased levels of a pro-inflammatory IgG receptor in the midbrain of people with schizophrenia
Journal of Neuroinflammation, 2022 Background There is growing evidence that neuroinflammation may contribute to schizophrenia neuropathology. Elevated pro-inflammatory cytokines are evident in the midbrain from schizophrenia subjects, findings that are driven by a subgroup of patients ...
A. Petty +8 more
doaj +1 more source
The search for new biomarkers for cognition in schizophrenia
Schizophrenia Research: Cognition, 2015 The search for biomarkers in cognition has been the focus of a large part of the research on patients suffering from schizophrenia. The scientific literature is heterogeneous, and few studies establishing an integrative model of pathogenesis and ...
Rafael Penadés +6 more
doaj +1 more source
Morbidity burden and community-based palliative care are associated with rates of hospital use by people with schizophrenia in the last year of life: A population-based matched cohort study [PDF]
, 2018 Objective: People with schizophrenia face an increased risk of premature death from chronic diseases and injury. This study describes the trajectory of acute care health service use in the last year of life for people with schizophrenia and how this ...
Arendts, Glenn +4 more
core +5 more sources
NeuroImage: Clinical, 2014 Heterogeneity in the structural brain abnormalities associated with schizophrenia has made identification of reliable neuroanatomical markers of the disease difficult.
Ian C. Gould +5 more
doaj +1 more source
Schizophrenia in older adults [PDF]
, 2011 Although the number of persons over the age of 55 with schizophrenia is expected to double over the next 20 years, the research data on older people with schizophrenia is limited.
American Psychiatric Association +12 more
core +2 more sources