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Schizophrenia [PDF]

The Lancet, 2016
Schizophrenia is a complex, heterogeneous behavioural and cognitive syndrome that seems to originate from disruption of brain development caused by genetic or environmental factors, or both. Dysfunction of dopaminergic neurotransmission contributes to the genesis of psychotic symptoms, but evidence also points to a widespread and variable involvement ...
A. Vita, S. Barlati, L. D. Peri, G. Deste, E. Sacchetti   +4 more
semanticscholar   +9 more sources

Schizophrenia [PDF]

The Lancet, 2022
Schizophrenia, characterised by psychotic symptoms and in many cases social and occupational decline, remains an aetiological and therapeutic challenge. Contrary to popular belief, the disorder is modestly more common in men than in women. Nor is the outcome uniformly poor.
Jauhar, Sameer, Johnstone, Mandy, McKenna, Peter J   +2 more
openaire   +3 more sources

Schizophrenia [PDF]

Medicine, 2012
Schizophrenia is a severe mental illness affecting several domains of cognition and behaviour. The illness most frequently becomes manifest in early adulthood, and often follows a chronic course. It is associated with high morbidity and mortality, and is a leading contributor to disease burden, health and social care costs throughout the world ...
Meyer, Nicholas, MacCabe, James H.
openaire   +7 more sources

Schizophrenia

Deutsches Ärzteblatt international, 2020
The lifetime prevalence of schizophrenia is 1%. Schizophrenia is among the most severe mental illnesses and gives rise to the highest treatment costs per patient of any disease. It is characterized by frequent relapses, marked impairment of quality of life, and reduced social and work participation.The group entrusted with the creation of the German ...
Hasan, Alkomiet, Falkai, Peter, Lehmann, Isabell, Gaebel, Wolfgang   +3 more
openaire   +6 more sources

Psychoeducation for schizophrenia [PDF]

Cochrane Database of Systematic Reviews, 2010
Schizophrenia can be a severe and chronic illness characterised by lack of insight and poor compliance with treatment. Psychoeducational approaches have been developed to increase patients' knowledge of, and insight into, their illness and its treatment.
Xia, Jun, Merinder, Lars Bertil, Belgamwar, Madhvi R   +2 more
openaire   +6 more sources

Biological Insights From 108 Schizophrenia-Associated Genetic Loci

Nature, 2014
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wide association studies.
S. Ripke, B. Neale, A. Corvin, J. Walters, Kai-How Farh, P. Holmans, Phil H. Lee, B. Bulik-Sullivan, D. Collier, Hailiang Huang, T. Pers, I. Agartz, E. Agerbo, M. Albus, Madeline Alexander, F. Amin, S. Bacanu, M. Begemann, R. Belliveau, J. Bene, Sarah L Bergen, Elizabeth Bevilacqua, T. Bigdeli, D. Black, R. Bruggeman, N. Buccola, R. Buckner, W. Byerley, W. Cahn, Guiqing Cai, D. Campion, R. Cantor, V. Carr, N. Carrera, S. Catts, K. Chambert, R. Chan, Ronald Y. L. Chan, E. Chen, Wei Cheng, E. Cheung, S. Chong, C. Cloninger, D. Cohen, Nadine Cohen, P. Cormican, N. Craddock, J. Crowley, D. Curtis, M. Davidson, K. Davis, F. Degenhardt, J. Del Favero, D. Demontis, D. Dikeos, T. Dinan, S. Djurovic, G. Donohoe, Elodie Drapeau, J. Duan, F. Dudbridge, N. Durmishi, P. Eichhammer, J. Eriksson, V. Escott-Price, L. Essioux, A. Fanous, M. Farrell, J. Frank, L. Franke, R. Freedman, N. Freimer, M. Friedl, J. Friedman, M. Fromer, G. Genovese, L. Georgieva, I. Giegling, P. Giusti-Rodríguez, S. Godard, J. Goldstein, V. Golimbet, S. Gopal, J. Gratten, L. de Haan, C. Hammer, M. Hamshere, M. Hansen, T. Hansen, V. Haroutunian, A. Hartmann, F. Henskens, S. Herms, J. Hirschhorn, P. Hoffmann, A. Hofman, M. Hollegaard, D. Hougaard, M. Ikeda, I. Joa, A. Julià, R. Kahn, L. Kalaydjieva, Sena Karachanak-Yankova, J. Karjalainen, D. Kavanagh, M. Keller, J. Kennedy, A. Khrunin, Yunjung Kim, J. Kloviņš, J. Knowles, B. Konte, V. Kučinskas, Z. Kučinskienė, Hana Kuzelova-Ptackova, A. Kähler, C. Laurent, Jimmy Lee, S. H. Lee, S. Legge, B. Lerer, Miaoxin Li, Tao Li, K. Liang, J. Lieberman, S. Limborska, C. Loughland, J. Lubiński, J. Lönnqvist, M. Macek, P. Magnusson, B. Maher, W. Maier, J. Mallet, S. Marsal, M. Mattheisen, M. Mattingsdal, R. McCarley, C. Mcdonald, A. McIntosh, S. Meier, C. Meijer, B. Melegh, I. Melle, R. Mesholam-Gately, A. Metspalu, P. Michie, L. Milani, V. Milanova, Y. Mokrab, D. Morris, O. Mors, K. Murphy, R. Murray, I. Myin‐Germeys, B. Müller-Myhsok, M. Nelis, I. Nenadić, D. Nertney, G. Nestadt, K. Nicodemus, L. Nikitina-Zake, L. Nisenbaum, Annelie Nordin, E. O'callaghan, C. O’Dushlaine, F. O’Neill, Sang-Yun Oh, A. Olincy, L. Olsen, J. van os, C. Pantelis, G. Papadimitriou, S. Papiol, E. Parkhomenko, M. Pato, T. Paunio, M. Pejović-Milovančević, D. Perkins, O. Pietiläinen, J. Pimm, A. Pocklington, J. Powell, A. Price, A. Pulver, S. Purcell, D. Quested, H. Rasmussen, A. Reichenberg, M. Reimers, A. Richards, J. Roffman, P. Roussos, D. Ruderfer, V. Salomaa, A. Sanders, U. Schall, C. Schubert, T. Schulze, S. Schwab, E. Scolnick, R. Scott, L. Seidman, Jianxin Shi, E. Sigurdsson, T. Silagadze, J. Silverman, K. Sim, P. Slominsky, J. Smoller, H. So, C. Spencer, E. Stahl, H. Stefánsson, S. Steinberg, E. Stogmann, R. Straub, E. Strengman, J. Strohmaier, T. Stroup, M. Subramaniam, J. Suvisaari, D. Svrakic, J. Szatkiewicz, E. Söderman, S. Thirumalai, D. Toncheva, S. Tosato, J. Veijola, J. Waddington, D. Walsh, Dai Wang, Qiang Wang, B. Webb, M. Weiser, D. Wildenauer, N. Williams, Stephanie Williams, S. Witt, A. Wolen, Emily H. M. Wong, B. Wormley, H. Xi, C. Zai, Xue-bin Zheng, F. Zimprich, N. Wray, K. Stefánsson, P. Visscher, R. Adolfsson, O. Andreassen, D. Blackwood, E. Bramon, J. Buxbaum, A. Børglum, S. Cichon, A. Darvasi, E. Domenici, H. Ehrenreich, T. Esko, P. Gejman, M. Gill, H. Gurling, C. Hultman, N. Iwata, A. Jablensky, E. Jönsson, K. Kendler, G. Kirov, J. Knight, T. Lencz, D. Levinson, Qingqin S. Li, Jianjun Liu, A. Malhotra, S. Mccarroll, A. McQuillin, J. Moran, P. Mortensen, B. Mowry, M. Nöthen, R. Ophoff, M. Owen, A. Palotie, C. Pato, T. Petryshen, D. Posthuma, M. Rietschel, B. Riley, D. Rujescu, P. Sham, P. Sklar, D. St. Clair, D. Weinberger, J. Wendland, T. Werge, M. Daly, P. Sullivan, M. O’Donovan   +299 more
semanticscholar   +1 more source

Cannabis and schizophrenia [PDF]

Cochrane Database of Systematic Reviews, 2014
Schizophrenia is a mental illness causing disordered beliefs, ideas and sensations. Many people with schizophrenia smoke cannabis, and it is unclear why a large proportion do so and if the effects are harmful or beneficial. It is also unclear what the best method is to allow people with schizophrenia to alter their cannabis intake.To assess the effects
Hannele Variend, Benjamin C McLoughlin, Katerina Kyprianou, John Rathbone, Jonathan A Pushpa-Rajah, Eliana Kalakouti, Donna Gillies   +6 more
openaire   +5 more sources

Búsqueda De Nuevos Biomarcadores De La Cognición En Esquizofrenia

Schizophrenia Research: Cognition, 2015
La búsqueda de biomarcadores en la cognición ha centrado una gran parte de las investigaciones en pacientes con esquizofrenia. La literatura científica es heterogénea y son escasos los estudios disponibles que permitan establecer un modelo integrador de ...
Rafael Penadés, Clemente Garcia-Rizo, Miquel Bioque, Alexandre González-Rodríguez, Bibiana Cabrera, Gisela Mezquida, Miquel Bernardo   +6 more
doaj   +1 more source

A nation-wide twin study of social cognition in schizophrenia spectrum disorders

npj Schizophrenia, 2022
We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ).
Cecilie K. Lemvigh, Birte Y. Glenthøj, Birgitte Fagerlund   +2 more
doaj   +1 more source

The search for new biomarkers for cognition in schizophrenia

Schizophrenia Research: Cognition, 2015
The search for biomarkers in cognition has been the focus of a large part of the research on patients suffering from schizophrenia. The scientific literature is heterogeneous, and few studies establishing an integrative model of pathogenesis and ...
Rafael Penadés, Clemente García-Rizo, Miquel Bioque, Alexandre González-Rodríguez, Bibiana Cabrera, Gisela Mezquida, Miquel Bernardo   +6 more
doaj   +1 more source