Results 191 to 200 of about 598,095 (375)

The next 10 years of behavioural genomic research

open access: yesJCPP Advances, Volume 2, Issue 4, December 2022., 2022
Three transformative developments for behavioural genomic research in the next 10 years are described. First, behavioural genomic research will use dimensional measures to reveal the hierarchical genetic architecture of psychopathology. A second direction for behavioural genomic research will be to investigate causa models of GE interplay.
Robert Plomin
wiley   +1 more source

Application of Artificial Intelligence in Schizophrenia Rehabilitation Management: A Systematic Scoping Review [PDF]

open access: yesarXiv
This systematic review assessed the current state and future prospects of artificial intelligence (AI) in schizophrenia rehabilitation management. We reviewed 61 studies on AI-related data types, feature engineering methods, algorithmic models, and evaluation metrics published from 2012-2024.
arxiv  

Current Status and Future Directions in the Development of Digital Therapeutic Interventions for Neurodevelopmental Disorders

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Innovations in digital technologies have emerged digital therapeutics (DTx) as a novel therapeutic intervention. DTx hold potential as novel theragnostics for disorders with broad diagnostic spectra, including neurodevelopmental diseases (NDDs). In this review, we highlight challenging factors in the successful development and deployment of DTx for ...
Hyun‐ju Lee   +11 more
wiley   +1 more source

Mapping gene by early life stress interactions on child subcortical brain structures: A genome‐wide prospective study

open access: yesJCPP Advances, Volume 2, Issue 4, December 2022., 2022
Although it is well‐established that both genetics and the environment influence brain development, they are typically examined separately. This study lends novel insights into gene‐environment interplay on the developing brain as well as pointing to promising candidate loci for future mechanistic studies.
Koen Bolhuis   +8 more
wiley   +1 more source

Automated Schizophrenia Detection from Handwriting Samples via Transfer Learning Convolutional Neural Networks [PDF]

open access: yesarXiv
Schizophrenia is a globally prevalent psychiatric disorder that severely impairs daily life. Schizophrenia is caused by dopamine imbalances in the fronto-striatal pathways of the brain, which influences fine motor control in the cerebellum. This leads to abnormalities in handwriting.
arxiv  

Nickel‐Catalyzed Hydro‐ and Deutero‐dehalogenations of (Hetero)Aryl Halides under Aqueous Micellar Catalysis Conditions

open access: yesChemSusChem, EarlyView.
Efficient Ni‐catalyzed hydrodehalogenations and deuterodehalogenations of aryl/heteroaryl halides are reported. This new technology applies to highly functionalized drugs and drug intermediates. The overall greenness is demonstrated via recyclability of the aqueous reaction media and associated overall low E‐Factors.
Monica S. Lopez Lemus   +5 more
wiley   +1 more source

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