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Psychiatric Clinics of North America, 1993
The pharmacologic treatment of the schizophrenic patient has remained substantively unchanged during the last 35 years. It is evident that as our knowledge of neuropharmacology has grown--the notion of schizophrenia being merely caused by a hyperdopaminergic state may be too simplistic.
S R, Marder +3 more
openaire +2 more sources
The pharmacologic treatment of the schizophrenic patient has remained substantively unchanged during the last 35 years. It is evident that as our knowledge of neuropharmacology has grown--the notion of schizophrenia being merely caused by a hyperdopaminergic state may be too simplistic.
S R, Marder +3 more
openaire +2 more sources
Current Opinion in Psychiatry, 2010
Although most guidelines recommend monotherapy in schizophrenia, the combined application of multiple psychotropic agents is very common, especially in treatment-refractory cases. We review the empirical basis supporting these attempts and their relevance for clinical practice.Polypharmacy intends to address different aspects of treatment resistance ...
M, Zink +2 more
openaire +3 more sources
Although most guidelines recommend monotherapy in schizophrenia, the combined application of multiple psychotropic agents is very common, especially in treatment-refractory cases. We review the empirical basis supporting these attempts and their relevance for clinical practice.Polypharmacy intends to address different aspects of treatment resistance ...
M, Zink +2 more
openaire +3 more sources