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The search for new biomarkers for cognition in schizophrenia

Schizophrenia Research: Cognition, 2015
The search for biomarkers in cognition has been the focus of a large part of the research on patients suffering from schizophrenia. The scientific literature is heterogeneous, and few studies establishing an integrative model of pathogenesis and ...
Rafael Penadés, Clemente García-Rizo, Miquel Bioque, Alexandre González-Rodríguez, Bibiana Cabrera, Gisela Mezquida, Miquel Bernardo   +6 more
doaj   +1 more source

Búsqueda De Nuevos Biomarcadores De La Cognición En Esquizofrenia

Schizophrenia Research: Cognition, 2015
La búsqueda de biomarcadores en la cognición ha centrado una gran parte de las investigaciones en pacientes con esquizofrenia. La literatura científica es heterogénea y son escasos los estudios disponibles que permitan establecer un modelo integrador de ...
Rafael Penadés, Clemente Garcia-Rizo, Miquel Bioque, Alexandre González-Rodríguez, Bibiana Cabrera, Gisela Mezquida, Miquel Bernardo   +6 more
doaj   +1 more source

Effectiveness of antipsychotic drugs in patients with chronic schizophrenia.

New England Journal of Medicine, 2005
BACKGROUND The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents has been incompletely addressed, though newer agents are currently used far more commonly.
J. Lieberman, T. Stroup, J. McEvoy, J. McEvoy, M. Swartz, R. Rosenheck, D. Perkins, R. Keefe, S. Davis, C. E. Davis, B. Lebowitz, J. Severe, J. Hsiao   +12 more
semanticscholar   +1 more source

Multivariate neuroanatomical classification of cognitive subtypes in schizophrenia: A support vector machine learning approach

NeuroImage: Clinical, 2014
Heterogeneity in the structural brain abnormalities associated with schizophrenia has made identification of reliable neuroanatomical markers of the disease difficult.
Ian C. Gould, Alana M. Shepherd, Kristin R. Laurens, Murray J. Cairns, Vaughan J. Carr, Melissa J. Green   +5 more
doaj   +1 more source

A nation-wide twin study of social cognition in schizophrenia spectrum disorders

npj Schizophrenia, 2022
We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ).
Cecilie K. Lemvigh, Birte Y. Glenthøj, Birgitte Fagerlund   +2 more
doaj   +1 more source

Differences in inflammatory marker profiles and cognitive functioning between deficit and nondeficit schizophrenia

Frontiers in Immunology, 2022
Deficit schizophrenia (DS) patient is a homogenous subtype of schizophrenia that includes primary and enduring negative symptoms. This study aimed to compare the differences in cognitive functioning and plasma levels of C-reactive protein (CRP) and ...
Dandan Wang, Yewei Wang, Yan Chen, Lingfang Yu, Zenan Wu, Ruimei Liu, Juanjuan Ren, Xinyu Fang, Chen Zhang   +8 more
doaj   +1 more source

Schizophrenia and the Dysfunctional Brain [PDF]

, 2010
Scientists, philosophers, and even the lay public commonly accept that schizophrenia stems from a biological or internal ‘dysfunction.’ However, this assessment is typically accompanied neither by well-defined criteria for ...
Garson, Justin
core   +1 more source

Grey-matter texture abnormalities and reduced hippocampal volume are distinguishing features of schizophrenia [PDF]

, 2014
Neurodevelopmental processes are widely believed to underlie schizophrenia. Analysis of brain texture from conventional magnetic resonance imaging (MRI) can detect disturbance in brain cytoarchitecture.
American Psychiatric Association, Andreasen, Annese, Arnold, Ashburner, Balaji Ganeshan, Cannon, Cannon, Chang, Chris Chatwin, de Oliveira, Eickhoff, Eugenia Radulescu, Fischl, Fornito, Ganeshan, Ganeshan, Goghari, Goldman, Gothelf, Gottesman, Groeschel, Gustavsson, Hafner, Harrison, Harrison, Harrison, Hilgetag, Hof, Honea, Hugo D. Critchley, Kassner, Kawasaki, Keshavan, Kovalev, Kubota, Kuhn, Kuperberg, Lemaitre, Mangin, Matthews, Meyer-Lindenberg, Nelson, Nesvag, Nick Medford, O’Daly, Prasad, Psychiatric Genomics Consortium, Qiu, Radulescu, Rasetti, Reif, Ridgway, Rimol, Rogers, Rorden, Rupert C.D. Young, Sanz-Cortes, Schmitt, Shenton, Shepherd, Sukhwinder S. Shergill, Tamminga, Theocharakis, Uranova, Van Essen, Weinberger, Weinberger, White, Wiegand, Wright, Yoon, Zhang, Zierhut   +73 more
core   +1 more source

Serotonin and schizophrenia [PDF]

, 2010
Abstract Although the serotonin hypothesis of schizophrenia is one of the oldest neurochemical hypotheses on the pathogenesis of the disease, it is still topical. The concept of how the serotonin system is involved in the origin and progress of schizophrenia has changed considerably over the past decades.
Quednow, Boris B, Geyer, Mark A, Halberstadt, Adam L   +2 more
openaire   +2 more sources

Hippocampal subregion abnormalities in schizophrenia: A systematic review of structural and physiological imaging studies. [PDF]

, 2018
AimThe hippocampus is considered a key region in schizophrenia pathophysiology, but the nature of hippocampal subregion abnormalities and how they contribute to disease expression remain to be fully determined.
Matsumoto, Mitsuyuki, Nakahara, Soichiro, van Erp, Theo GM   +2 more
core   +1 more source