Results 11 to 20 of about 200,189 (245)

Schizophrenia [PDF]

The Lancet, 2016
Schizophrenia is a complex, heterogeneous behavioural and cognitive syndrome that seems to originate from disruption of brain development caused by genetic or environmental factors, or both. Dysfunction of dopaminergic neurotransmission contributes to the genesis of psychotic symptoms, but evidence also points to a widespread and variable involvement ...
Michael J Owen, Akira Sawa, Preben B Mortensen   +2 more
openaire   +8 more sources

Schizophrenia

New England Journal of Medicine, 2020
The lifetime prevalence of schizophrenia is 1%. Schizophrenia is among the most severe mental illnesses and gives rise to the highest treatment costs per patient of any disease. It is characterized by frequent relapses, marked impairment of quality of life, and reduced social and work participation.The group entrusted with the creation of the German ...
Matthew L, Goldman, Harold A, Pincus, Christina, Mangurian   +2 more
openaire   +7 more sources

Schizophrenia

The Lancet, 2022
Schizophrenia, characterised by psychotic symptoms and in many cases social and occupational decline, remains an aetiological and therapeutic challenge. Contrary to popular belief, the disorder is modestly more common in men than in women. Nor is the outcome uniformly poor.
Jauhar, Sameer, Johnstone, Mandy, McKenna, Peter J   +2 more
openaire   +3 more sources

Clinical Utility and Lifespan Profiling of Neurological Soft Signs in Schizophrenia Spectrum Disorders [PDF]

, 2016
Neurological soft signs (NSSs) bear the promise for early detection of schizophrenia spectrum disorders. Nonetheless, the sensitivity and specificity of NSSs in the psychosis continuum remains a topic of controversy.
Yu, Xin, Chan, Raymond C. K., Wang, Chuan-yue, Rosenthal, Robert, Wang, Ya, Chan, Raymond C.K., Lui, Simon SY, Cheung, Eric F.C., Geng, Fu Lei, Wang, Chuan Yue, Xie, Weizhen, Geng, Fu-lei, Cheung, Eric F. C., Chan, Raymond CK, Cheung, Eric FC, Lui, Simon S. Y., Lui, Simon S.Y.   +16 more
core   +1 more source

Multivariate neuroanatomical classification of cognitive subtypes in schizophrenia: A support vector machine learning approach

NeuroImage: Clinical, 2014
Heterogeneity in the structural brain abnormalities associated with schizophrenia has made identification of reliable neuroanatomical markers of the disease difficult.
Ian C. Gould, Alana M. Shepherd, Kristin R. Laurens, Murray J. Cairns, Vaughan J. Carr, Melissa J. Green   +5 more
doaj   +1 more source

Cardiovascular Diseases and Schizophrenia in India: Evidence, Gaps, and Way Forward

Frontiers in Psychiatry, 2021
Background: The importance of physical health among persons with schizophrenia is well-established. Studies from developed and developing countries indicated a strong association between cardiovascular diseases and schizophrenia, while evidence from ...
Ramachandran Padmavati, Suvarna Jyothi Kantipudi, Suhavana Balasubramanian, Vijaya Raghavan   +3 more
doaj   +1 more source

A nation-wide twin study of social cognition in schizophrenia spectrum disorders

npj Schizophrenia, 2022
We examined social cognition in 32 monozygotic (MZ) and 21 dizygotic (DZ) twin pairs concordant or discordant for a schizophrenia spectrum diagnosis and healthy control (HC) twin pairs (29 MZ/20 DZ).
Cecilie K. Lemvigh, Birte Y. Glenthøj, Birgitte Fagerlund   +2 more
doaj   +1 more source

Novel Schizophrenia Risk Gene TCF4 Influences Verbal Learning and Memory Functioning in Schizophrenia Patients [PDF]

, 2011
Background: Recently, a role of the transcription factor 4 (TCF4) gene in schizophrenia has been reported in a large genome-wide association study. It has been hypothesized that TCF4 affects normal brain development and TCF4 has been related to different
Lennertz, Leonhard, Wölwer, Wolfgang, Leonhard Lennertz, Gaebel, Wolfgang, Häfner, Heinz, Möller, Hans-Jürgen, Maier, Wolfgang, Heinz Häfner, Michael Wagner, Dan Rujescu, Svenja Schulze-Rauschenbach, Anna Schuhmacher, Wagner, Michael, Petra Franke, Ingo Frommann, Wolfgang Gaebel, Wolfgang Maier, Schulze-Rauschenbach, Svenja, Rainald Mössner, Schuhmacher, Anna, Wolfgang Wölwer, Martin W. Landsberg, Landsberg, Martin W., Hans-Jürgen Möller, Franke, Petra, Mössner, Rainald, Rujescu, Dan, Frommann, Ingo   +27 more
core   +1 more source

Avatar Therapy for people with schizophrenia or related disorders [PDF]

, 2020
BackgroundMany people with schizophrenia do not achieve satisfactory improvements in their mental state, particularly the symptom of hearing voices (hallucinations), with medical treatment.ObjectivesTo examine the effects of Avatar Therapy for people ...
Aali, Ghazaleh, Shokraneh, Farhad, Kariotis, Timothy, Aali, G, Shokraneh, F, Kariotis, T   +5 more
core   +1 more source

Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis [PDF]

, 2000
Objective To develop an evidence base for recommendations on the use of atypical antipsychotics for patients with schizophrenia.Design Systematic overview and meta-regression analyses of randomised controlled trials, as a basis for formal development of ...
Freemantle, Nick, Geddes, J, Freemantle, N, Bebbington, P, Harrison, P, Natl Schizophrenia Guideline Dev   +5 more
core   +1 more source