Results 101 to 110 of about 77,423 (292)

Engineering Strategies for Fungal Cell Disruption in Biotechnological Applications

Engineering in Life Sciences, Volume 25, Issue 12, December 2025.
ABSTRACT Fungal cell disruption plays a critical role in unlocking a wide range of high‐value intracellular products such as lipids, proteins, pigments, and bioactive compounds. However, lysing fungal cells is far more challenging than breaking bacterial or algal cells due to their robust and highly structured cell walls.
Bhagyeshri Ulhas Mantri, Maliheh Vahidinasab, Sonja Berensmeier   +2 more
wiley   +1 more source

Schizosaccharomyces pombe as a predictor toxicity tool

MethodsX
The fission yeast Schizosaccharomyces pombe is frequently used as a genetically manipulable model system, offering valuable understandings into cellular mechanisms.
Consuelo Álvarez-Herrera, Sara Maisanaba, María Llana Ruíz-Cabello, Guillermo Repetto   +3 more
doaj   +1 more source

Tv-RIO1 – an atypical protein kinase from the parasitic nematode Trichostrongylus vitrinus [PDF]

, 2008
Background: Protein kinases are key enzymes that regulate a wide range of cellular processes, including cell-cycle progression, transcription, DNA replication and metabolic functions. These enzymes catalyse the transfer of phosphates to serine, threonine
Gasser, Robin B., Hu, Min, LaRonde-LeBlanc, Nicole, Sternberg, Paul W.   +3 more
core   +6 more sources

Dysbiosis and Therapeutic Modulation of the Gut Microbiota in Multiple Sclerosis: A Narrative Review

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Multiple sclerosis (MS) is a persistent autoimmune disease that affects the central nervous system. The etiology of MS is complex, involving a variety of genetic and environmental factors. Mounting evidence suggests that dysbiosis significantly impacts the progression of MS mainly through its direct effects upon the immune ...
Mojtaba Memariani, Hamed Memariani
wiley   +1 more source

In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells. [PDF]

, 1990
To investigate the mechanisms of spindle elongation and chromosome separation in the fission yeast Schizosaccharomyces pombe, we have developed an in vitro assay using a temperature-sensitive mutant strain, nuc2.
Cande, WZ, Hirano, T, Masuda, H, Yanagida, M   +3 more
core  

Holliday junction resolvase in Schizosaccharomyces pombe has identical endonuclease activity to the CCE1 homologue YDC2 [PDF]

, 1998
A novel Holliday junction resolving activity has been identified in fractionated cell extracts of the fission yeast Schizosaccharomyces pombe . The enzyme catalyses endonucleolytic cleavage of Holliday junction-containing chi DNA and synthetic four-way ...
Keeley, A, Oram, M, Tsaneva, IR
core   +2 more sources

Computational systems biology approaches to cellular aging—Integrating network maps and dynamical models

Quantitative Biology, Volume 13, Issue 4, December 2025.
Abstract Cellular aging is a multifaceted complex process. Many genes and factors have been identified that regulate cellular aging. However, how these genes and factors interact with one another and how these interactions drive the aging processes in single cells remain largely unclear.
Hetian Su, Nan Hao
wiley   +1 more source

Interspecies conservation of organisation and function between nonhomologous regional centromeres

Nature Communications, 2019
Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that ...
Pin Tong, Alison L. Pidoux, Nicholas R. T. Toda, Ryan Ard, Harald Berger, Manu Shukla, Jesus Torres-Garcia, Carolin A. Müller, Conrad A. Nieduszynski, Robin C. Allshire   +9 more
doaj   +1 more source

Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2 [PDF]

Open Biology, 2016
Cell proliferation, metabolism, migration and survival are coordinated through the tight control of two target of rapamycin (TOR) kinase complexes: TORC1 and TORC2.
Wei Du, Gabriella M. Forte, Duncan Smith, Janni Petersen   +3 more
doaj   +1 more source

From Yeast to Therapeutics: Modeling Neurodegenerative Diseases in Saccharomyces cerevisiae

Yeast, Volume 42, Issue 12, Page 283-302, December 2025.
Yeast plasmids expressing human Aβ‐42, α‐syn, htt, and TDP‐43. Their fate includes an equilibrium between the endocytic pathway and aggregates that potentially disrupt endocytosis, vesicular transport, vacuolar autophagy, and mitochondrial activity. ABSTRACT Here, we review the use of Saccharomyces cerevisiae as a powerful model organism for studying ...
Jose Ribamar Ferreira‐Junior, Vittoria de Lima Camandona, Mario H. Barros   +2 more
wiley   +1 more source