Results 31 to 40 of about 64,699 (203)

Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels

eLife, 2020
Cytokinesis, which enables the physical separation of daughter cells once mitosis has been completed, is executed in fungal and animal cells by a contractile actin- and myosin-based ring (CAR).
Elisa Gómez-Gil, Rebeca Martín-García, Jero Vicente-Soler, Alejandro Franco, Beatriz Vázquez-Marín, Francisco Prieto-Ruiz, Teresa Soto, Pilar Pérez, Marisa Madrid, Jose Cansado   +9 more
doaj   +1 more source

Distinct requirements for the Rad32(Mre¹¹) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA [PDF]

, 2009
For a cancer cell to resist treatment with drugs that trap topoisomerases covalently on the DNA, the topoisomerase must be removed. In this study, we provide evidence that the Schizosaccharomyces pombe Rad32Mre11 nuclease activity is involved in the ...
Akamatsu, Antony M. Carr, Baldwin, Champoux, Connelly, Connelly, Edgar Hartsuiker, El-Khamisy, Farah, Gutz, Hartsuiker, Hopfner, Hopfner, Keeney, Keeney, Krogh, Krogh, Lengsfeld, Limbo, Liu, Malik, Matthew J. Neale, McKee, Miyoshi, Moreau, Neale, Nitiss, Osheroff, Porter, Pouliot, Prinz, Sartori, Shaw, Stracker, Subramanian, Takashima, Tomita, Utsugi, Young   +38 more
core   +2 more sources

The role of Schizosaccharomyces pombe SUMO ligases in genome stability [PDF]

, 2007
SUMOylation is a post-translational modification that affects a large number of proteins, many of which are nuclear. While the role of SUMOylation is beginning to be elucidated, it is clear that understanding the mechanisms that regulate the process is ...
A. Skilton, al-Khodairy, Allshire, Allshire, Andrews, Apionishev, Branzei, Chakrabarti, Cheng, E.A. Outwin, Ekwall, F.-X. Ogi, F.Z. Watts, Grishchuk, Ho, Ho, Hoege, Hooker, J.C.-Y. Ho, Johnson, Kagey, Kahyo, L. Gardner, L.K. Boyd, M.A.M. Trickey, McDonald, Okubo, Pichler, Potts, Reindle, Sachdev, Schmidt, Sergeant, Shayeghi, Shin, Stelter, Strahl-Bolsinger, Tanaka, Taylor, Thon, Watts, Xhemalce, Xhemalce, Zhao, Zhao   +44 more
core   +2 more sources

Role for the fission yeast RecQ helicase in DNA repair in G2. [PDF]

, 2003
Members of the RecQ helicase subfamily are mutated in several human genomic instability syndromes, such as Bloom, Werner, and Rothmund-Thomson syndromes. We show that Rqh1, the single Schizosaccharomyces pombe homologue, is a 3'-to-5' helicase and exists
Ampatzidou, Eleni, Andersen, Anni H, Laursen, Louise V, Murray, Johanne M   +3 more
core   +3 more sources

Unexpected insertion of carrier DNA sequences into the fission yeast genome during CRISPR–Cas9 mediated gene deletion

BMC Research Notes, 2019
Objectives The fission yeast Schizosaccharomyces pombe is predicted to encode ~ 200 proteins of 
Sophie Longmuir, Nabihah Akhtar, Stuart A. MacNeill   +2 more
doaj   +1 more source

Complete sequences of Schizosaccharomyces pombe subtelomeres reveal multiple patterns of genome variation

Nature Communications, 2021
Sequencing and mapping of long repetitive regions can be challenging due to technical difficulties in sequencing and assembly of the sequence data. Here authors report the complete sequences of subtelomeric homologous (SH) regions of the fission yeast ...
Yusuke Oizumi, Takuto Kaji, Sanki Tashiro, Yumiko Takeshita, Yuko Date, Junko Kanoh   +5 more
doaj   +1 more source

Produksi Etanol Proses Sinambung dengan Schizosaccharomyces Pombe

Jurnal Rekayasa Kimia & Lingkungan, 2009
Ethanol is one of fermentation products which are mostly used as solvent in pharmaceutical and chemical industries. Ethanol production by fermentation generally uses yeast from Saccharomyces and Schizosaccharomyces.
Panca Nugrahini Febriningrum
doaj   +2 more sources

The Rad4TopBP1 ATR-Activation domain functions in G1/S phase in a chromatin-dependent manner [PDF]

, 2012
DNA damage checkpoint activation can be subdivided in two steps: initial activation and signal amplification. The events distinguishing these two phases and their genetic determinants remain obscure.
Carr, Antony, Caspari, Thomas, Chahwan, Charly, Garcia, Valerie, Lin, Su-Jiun, Miyabe, Izumi, Morishita, Takashi, Schmidt, Ulrike, Wardlaw, Christopher Paul   +8 more
core   +9 more sources

Single-step Marker Switching in Schizosaccharomyces pombe Using a Lithium Acetate Transformation Protocol

Bio-Protocol, 2016
The ability to utilize different selectable markers for tagging or mutating multiple genes in Schizosaccharomyces pombe is hampered by the historical use of only two selectable markers, ura4+ and kanMX6; the latter conferring resistance to the antibiotic
Simon Brown, Alexander Lorenz
doaj   +1 more source

Spd2 assists Spd1 in modulation of RNR architecture but does not regulate deoxynucleotide pools [PDF]

, 2014
In yeasts, small intrinsically disordered proteins (IDPs) modulate ribonucleotide reductase (RNR) activity to ensure an optimal supply of dNTPs for DNA synthesis. The S. pombe Spd1 protein can directly inhibit the large RNR subunit (R1), import the small
Basrai, Beck, Bester, Bähler, Chabes, Danielsson, Elledge, Fairman, Fleck, Halazonetis, Hofer, Holmberg, Holmberg, Håkansson, Kjaerulff, Knutsen, Lee, Liu, Liu, Marguerat, Maundrell, Moreno, Moss, Nestoras, Nielsen, Nordlund, Reichard, Rhind, Salguero, Tompa, Uchiki, Weinberg, Woollard, Wu, Yoshida, Zhao, Zhao, Zolezzi   +37 more
core   +1 more source