Results 41 to 50 of about 42,218 (167)

Benzoic acid inhibits Coenzyme Q biosynthesis in Schizosaccharomyces pombe.

open access: yesPLoS ONE, 2020
Coenzyme Q (CoQ, ubiquinone) is an essential component of the electron transport system in aerobic organisms. Human type CoQ10, which has 10 units of isoprene in its quinone structure, is especially valuable as a food supplement.
Ikuhisa Nishida   +4 more
doaj   +1 more source

Selected Schizosaccharomyces pombe Strains Have Characteristics That Are Beneficial for Winemaking. [PDF]

open access: yesPLoS ONE, 2016
At present, wine is generally produced using Saccharomyces yeast followed by Oenococus bacteria to complete malolactic fermentation. This method has some unsolved problems, such as the management of highly acidic musts and the production of potentially ...
Ángel Benito   +6 more
doaj   +1 more source

Silver nanoparticles elevate mutagenesis of eukaryotic genomes

open access: yesG3: Genes, Genomes, Genetics, 2023
Metal nanoparticles, especially silver, have been used in various medical scenarios, due to their excellent antimicrobial effects. Recent studies have shown that AgNPs do not exert mutagenic effects on target bacteria, but the degree to which they ...
Kun Wu   +7 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

MCM-GINS and MCM-MCM interactions in vivo visualised by bimolecular fluorescence complementation in fission yeast [PDF]

open access: yes, 2009
Background: Each of the three individual components of the CMG complex (Cdc45, MCM and GINS) is essential for chromosomal DNA replication in eukaryotic cells, both for the initiation of replication at origins and also for normal replication fork ...
Gökhan Akman   +6 more
core   +1 more source

Combinatorial Tuning of Multigene Biosynthetic Pathways based on RNA Interference

open access: yesAdvanced Science, EarlyView.
Small RNA sequencing identifies candidate endogenous Pol III promoters, and subsequent fluorescence screening measures knockdown efficiency to assess promoter strength. Combining promoter strength and shRNA target position enables fine‐grained RNAi regulation of multigene pathways. This strategy enhances β‐carotene production in Schizochytrium sp.
Zixu Zhang   +6 more
wiley   +1 more source

Explaining lengths and shapes of yeast by scaling arguments. [PDF]

open access: yesPLoS ONE, 2009
Lengths and shapes are approached in different ways in different fields: they serve as a read-out for classifying genes or proteins in cell biology whereas they result from scaling arguments in condensed matter physics.
Daniel Riveline
doaj   +1 more source

Microtubule Destabilizing Kinesins: A Historical Perspective and Thoughts for the Future

open access: yesCytoskeleton, EarlyView.
ABSTRACT The microtubule cytoskeleton plays critical roles in multiple cellular processes such as mitotic spindle assembly and chromosome segregation. Cells contain a number of microtubule‐associated proteins that regulate microtubule dynamics both temporally and spatially in cells. The microtubule depolymerizing kinesins include members of the Kinesin‐
Claire E. Walczak
wiley   +1 more source

Schizosaccharomyces pombe strains.

open access: yes, 2013
Schizosaccharomyces pombe strains.
Sean M. Hemmingsen (119052)   +3 more
core   +1 more source

Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosaccharomyces pombe. [PDF]

open access: yesPLoS ONE, 2012
The ERH gene encodes a highly conserved small nuclear protein with a unique amino acid sequence and three-dimensional structure but unknown function. The gene is present in animals, plants, and protists but to date has only been found in few fungi.
Marek K Krzyzanowski   +2 more
doaj   +1 more source

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