Results 61 to 70 of about 6,783,038 (332)
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
School-building architecture of the Russian provinces. Late 19th – early 20th century
АрхитектонBased on publications in the magazines “Zodchiy” (The Architect) and “Stroitel” (The Builder) (1896-1905), the article offers an overview of how educational institutions of junior and middle levels developed in the provincial cities of the Russian Empire
Ivanova Alina P.
doaj +1 more source
The educationalization of school architecture in Switzerland between 1840 and 1950
Historia y Memoria de la Educación, 2021 This paper analyses and contrasts the evolution of school architecture competitions, selected submitted projects and built schoolhouses, programmatic and professional literature, school building exhibitions and public reactions to them aiming at ...
Marianne Helfenberger
doaj +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Building a Better World with Carl Elefante [PDF]
, 2019 Carl Elefante, 2018 president of the AIA, spoke at an evening event on March 28th and provided mentorship to an architecture studio class on the 29th. Elefante believes students in the School of Architecture, Art and Historic Preservation (SAAHP) are at
Rubin, Julia
core +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Organisation de l’espace scolaire et formation de l’identité chez les adolescents
Revue Internationale d’Éducation de Sèvres, 2013 This article examines the relationship between school design and adolescent identity formation. The literature and empirical studies identify three major processes involved in forming this identity: separation or individuation process; social integration
Neda Abbasi
doaj +1 more source
Reconnecting Schools and Neighborhoods: A proposal for School Centered Community Revitalization in Baltimore Maryland [PDF]
, 2008 This project explores the concept of school-centered community as a key aspect in assisting urban renewal through architecture. It employs this concept through the architectural design of a middle school in Baltimore, Maryland that has a focus on music ...
Miller, Cody
core +1 more source