Results 81 to 90 of about 1,101,051 (314)
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
A Methodology for Integrated Refurbishment Actions in School Buildings
Buildings, 2018 Educational buildings could play leading roles in increasing high-performance building refurbishments across Europe. The city of Vienna has substantially modernized its schools in the last decade, however mostly single refurbishment measures have been ...
Doris Österreicher
doaj +1 more source
Conservation and modern architecture. Fortune and misfortune of the School of Mathematics at Rome University (G. Ponti, 1932-1935) [PDF]
, 2015 The framework of the Italian restoration doctrine is based on the reception and transmission of the memory of the past. However, interventions in modern architecture represent a radical drift in the sense that they mostly consist of reconstructions ...
SALVO, Simona Maria Carmela
core
Assessment of Significant Causes to School Building Defects [PDF]
, 2014 This paper focuses on the contribution factors of building defects in Malaysian school buildings. There are several building defects commonly found in Malaysia school buildings.
Agus Salim, N.A. +4 more
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
An anomaly detection method for identifying locations with abnormal behavior of temperature in school buildings. [PDF]
Sci Rep, 2023 Wickramasinghe A +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source