Results 61 to 70 of about 1,101,051 (314)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Formation of silicic crust on early Earth and young planetary bodies in an Iceland-like setting
Communications Earth & EnvironmentFour billion years ago, Earth’s surface was covered with a thick basaltic crust and, similar to other rocky planets and the Moon, parts of this basaltic crust underwent partial melting to produce silicic crust.
Sally Law +3 more
doaj +1 more source
Improving energy efficiency of school buildings during winter season using passive design strategies
Sustainable Buildings, 2020 Passive building design can improve energy efficiency of buildings, while providing comfortable indoor environment for occupants with minimum mechanical energy use.
Zahiri Sahar, Altan Hasim
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
School Building Surveying: A Support Tool for School Building Registry Office [PDF]
, 2019 On the national territory, the school building situation appears patchy, with very different situations in several respects, the most important of which is related to structural safety, to possessing the correct certification for fire prevention or hygiene.
Monestiroli, T. +4 more
openaire +4 more sources
Energy Performance and Thermal Comfort in Madrid School Buildings Under Climate Change Scenarios
Applied SciencesThis study presents a detailed analysis of the energy performance and thermal comfort conditions in four existing school buildings located in Madrid, Spain.
Violeta Rodríguez-González +1 more
doaj +1 more source
Shuttered Public Schools: The Struggle to Bring Old Buildings New Life [PDF]
, 2013 Large-scale public school closures have become a fact of life in many American cities, and that trend is not likely to stop now. This report looks at what happens to the buildings themselves, studying the experiences of Philadelphia and 11 other cities ...
Emily Dowdall, Susan Warner
core
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Learning through prefabrication [PDF]
, 2008 The use of prefabrication in design exemplar houses has escalated in Australia in the past decade. The same level of design quality has not been applied to the design of prefabricated school buildings.
Newton, Clare
core +1 more source
Building Capacity in Struggling Schools [PDF]
Educational Practice and Theory, 2004 The ‘School Facing Exceptionally Challenging Circumstances’ pilot project funded by the DFES includes provision for flexibility in the application of the National Curriculum, a reading programme to support non-fluent readers in Year 7 and Year 8, (i.e.
openaire +1 more source