Results 101 to 110 of about 398,034 (315)

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

Advanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura, Hiroyoshi Y. Tanaka, Mayu Ohira, Haruko Ohta‐Okano, Reika Nakamura, Yu Seno, Saaya Yara, Sakura Fujita, Daichi Shibata, Masaya Yamamoto, Shinichi Toyooka, Kensuke Osada, Horacio Cabral, Atsushi Masamune, Mitsunobu R. Kano   +14 more
wiley   +1 more source

Evaluating Success of Pediatric Dentistry Department at Mashhad Dental School (Iran) in Clinical Skills Education from Students’ Perspectives [PDF]

Journal of Mashhad Dental School
Introduction: Periodic evaluation of educational programs provides insight into the course and teaching effectiveness. Effective evaluation provides valuable information, which contributes to both student’s and course success.
Hosein Nematollahi, Lila Razeei, Razie Khanmohammadi, Hojat Shakib   +3 more
doaj  

Attitude of Parents Referred to the Department of Pediatric Dentistry towards Different Behavioral Management Techniques Used in Pediatric Dentistry

Journal of Dental School, 2019
Objective: Behavior management of uncooperative children is an important principle in pediatric dentistry. By adopting an appropriate behavior management technique, pediatric dentists can treat patients more effectively and create a positive attitude ...
Mahdi Jafarzadeh, Fahimeh Kooshki, Beheshteh Malekafzali, Soudabeh Ahmadi   +3 more
doaj   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

The Relationship Between Primary Sleep Disorders and Temporomandibular Disorders: An 8-Year Nationwide Cohort Study in South Korea

International Journal of General Medicine, 2021
Seon-Jip Kim,1,2 Sang Min Park,3,4 Hyun-Jae Cho,1,2,* Ji Woon Park2,5,6,* 1Department of Preventive Dentistry and Public Oral Health, School of Dentistry, Seoul National University, Seoul, Republic of Korea; 2Dental Research Institute, Seoul ...
Kim SJ, Park SM, Cho HJ, Park JW
doaj  

Complete Mouth Rehabilitation and Gastroesophageal Reflux Disease: Conventional and Contemporary Treatment Approaches [PDF]

, 2017
This report describes the diagnosis and prosthodontic management of 2 patients with a history of chronic gastroesophageal reflux disease and worn dentition. Different treatment approaches were used for oral rehabilitation.
Chronopoulos, Vasilios, Maroulakos, Georgios, Nagy, William W., Stathopoulou, Panagiota, Tsoutis, Konstantinos   +4 more
core   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source

The Methodological Evaluation of General Dentistry Students’ Theses in Shiraz Dentistry School (2006-2008) [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2012
Introduction: Considering the impact of dissertations on students’ improvement in scientific knowledge and regarding the fact that methodology is the cornerstone of every research endeavor the present study aimed to investigate the research methodology ...
Ladan Zarshenas, Soheila Shaghaghian, Shahla Momeni danaei, Seyed hamid reza Tabatabaei   +3 more
doaj  

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

The Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum, Michael J. Blumer, Mason N. Dean, Laura J. Ekstrom   +3 more
wiley   +1 more source

The Impact of COVID-19 Pandemic on the Psychological Health and Dental Practice of Oral Healthcare Workers: A Scoping Review

Risk Management and Healthcare Policy, 2022
Farooq Ahmad Chaudhary,1 Ayesha Fazal,1 Basaruddin Ahmad,2 Osama Khattak,3 Mawra Hyder,1 Muhammad Mohsin Javaid,1 Azhar Iqbal,3 Rakhi Issrani4 1Department of Community Dentistry, School of Dentistry (SOD), Federal Medical Teaching Institution (FMTI)/PIMS,
Chaudhary FA, Fazal A, Ahmad B, Khattak O, Hyder M, Javaid MM, Iqbal A, Issrani R   +7 more
doaj