Results 141 to 150 of about 9,109,070 (367)

INCORPORATING CEFR PRINCIPLES IN THE DEVELOPMENT OF A HYPERTEXT POETRY LEARNING PLATFORM FOR HIGH SCHOOL STUDENTS

, 2023
Sinta Indriyani, Lala Bumela Sudimantara
openalex   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Development Of Self Construction Animation Software To Improve The Quality Of Science Instructional In Junior High School [PDF]

, 2017
Diana Rochintaniawati, Rika Rafikah Agustin, Yayan Sanjaya   +2 more
openalex   +1 more source

PENGEMBANGAN BAHAN AJAR DIGITAL INTERAKTIF INTEGRATIF PEMBELAJARAN MENULIS TEKS EKSPOSISI KELAS X SMA [PDF]

The competence of the 21st century in the era of the industrial revolution requires the integration of information and communication technology in the world of education so that the selection of teaching materials must also be adjusted to the demands of ...
Zuhria, Kholilatuz
core  

Investigating a Professional Development School Model of Teacher Education in Canada [PDF]

, 2013
We examined the effectiveness of a professional development school model of teacher education in Canada. Teacher education candidates responded positively to program features related to sustained participation and collaboration in school communities ...
Buzza, Dawn, Johnston, Megan E., Kotsopoulos, Donna, Mueller, Julie   +3 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Development of a Model for Natural Disaster Mitigation on the Socialization in Elementary School

, 2017
Ruslan Dabi, Rugaya M Pandawa, Damir Umanailo, Irwan Abdullah, M Andrew, J Boyle, J Iskandar, Jacobs Jackson, S Oemarmadi, I Subiyantoro   +9 more
openalex   +1 more source

The Development of COLESTVIAModel as An Effort of Internanalization of Character Values in Social Studies [PDF]

, 2013
Purpose: This research is based on a condition of Social Studies instruction in Junior High schools in Surakarta that is still far from the expectation. It focuses on the cognitive aspect and lack of affective aspects. Therefore, it is important to
Agung S., Leo
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

DEVELOPMENT OF SCHOOL AS ORGANIZATION – HOW SCHOOL LEADERS UNDERSTAND IT

INTED Proceedings, 2019
Educational leadership theory still needs adequate development in order to satisfy needs of complex and rapidly changing school context. It seems that best attempts of such theories are those underlying the central role of a person (Fielding, 2006) and its individual development (Dorczak, 2012).
openaire   +2 more sources