Results 51 to 60 of about 5,214 (210)

Academic Goals and Attitudes Towards Institutional Authority: A Relationship Mediated by Life Satisfaction and Sense of Belonging to the School

European Journal of Investigation in Health, Psychology and Education
Academic success is conditioned by different factors, related to academic goals, life satisfaction, and feelings of belonging to the school. This article aims to assess whether beliefs, attributions (academic goals), and feelings (life satisfaction and ...
Laura Giaquinto, Roberto Sanz, Pau García-Grau   +2 more
doaj   +1 more source

Aquisição de leitura e escrita como resultado do ensino de habilidades de consciência fonológica Reading and writing acquisition as a result of teaching phonological awareness abilities

Revista Brasileira de Educação Especial, 2006
Quatro estudantes com dificuldades na aquisição de leitura e escrita foram submetidos a um programa de ensino para o desenvolvimento de habilidades de consciência fonológica, com tarefas de identificação de rima e aliteração e análise e síntese silábica ...
José Antonio Bernardino Júnior, Fabiana Rego Freitas, Deisy G. de Souza, Elisandra André Maranhe, Heloisa Helena Motta Bandini   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

FATHERS’ IMPORTANCE IN ADOLESCENTS’ ACADEMIC ACHIEVEMENT

International Journal of Child, Youth & Family Studies, 2018
Many studies have investigated mothers’ impact on students’ achievement, yet little is known about how various father types impact students’ school performance.
Stephen D. Whitney, Sara Prewett, Ze Wang, Haiqin Chen   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

ROMANIAN EDUCATION SYSTEM SYNCOPEʼS REVEALED BY PISA TESTS. CAUSES OF SCHOOL FAILURE AND POSSIBLE AMELIORATIVE INTERVENTIONS [PDF]

Studia Universitatis Babeş-Bolyai. Psychologia-Paedagogia, 2012
. PISA type tests involving Romanian students in 2000 and until now have led to poor results, highlighting that the education system in Romania has many weaknesses. The national test results are not satisfactory.
ION ALBULESCU, MIRELA ALBULESCU
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source