Results 51 to 60 of about 11,439,196 (292)

Naval Postgraduate School Foundation Homepage

, 2014
Screenshot of the Naval Postgraduate School Foundation website.Homepage of the Naval Postgraduate School ...
Naval Postgraduate School Foundation
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Éducation inclusive, réussite scolaire et passage à l’âge adulte

Populations Vulnérables, 2013
Cet article analyse les conditions de scolarisation de lycéens danois, français, néerlandais et tchèques inscrits en 2007 en terminale et interroge l’aptitude des systèmes éducatifs à placer les élèves à besoins éducatifs particuliers (BEP) à égalité de ...
Serge Ebersold
doaj   +1 more source

Dynamics of Visual Partial Functions in Children and Pupils from 5-8 Years of Age [PDF]

Клиническая и специальная психология, 2019
The article focuses on the structure and the dynamics of partial functions of visual skills (visual segmentation – visual differentiation of the figure/background, visual differentiation of shapes and visual memory) children during their last year at ...
Valenta M.
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Academic Goals and Attitudes Towards Institutional Authority: A Relationship Mediated by Life Satisfaction and Sense of Belonging to the School

European Journal of Investigation in Health, Psychology and Education
Academic success is conditioned by different factors, related to academic goals, life satisfaction, and feelings of belonging to the school. This article aims to assess whether beliefs, attributions (academic goals), and feelings (life satisfaction and ...
Laura Giaquinto, Roberto Sanz, Pau García-Grau   +2 more
doaj   +1 more source

Aquisição de leitura e escrita como resultado do ensino de habilidades de consciência fonológica Reading and writing acquisition as a result of teaching phonological awareness abilities

Revista Brasileira de Educação Especial, 2006
Quatro estudantes com dificuldades na aquisição de leitura e escrita foram submetidos a um programa de ensino para o desenvolvimento de habilidades de consciência fonológica, com tarefas de identificação de rima e aliteração e análise e síntese silábica ...
José Antonio Bernardino Júnior, Fabiana Rego Freitas, Deisy G. de Souza, Elisandra André Maranhe, Heloisa Helena Motta Bandini   +4 more
doaj   +1 more source