Results 61 to 70 of about 3,336,539 (310)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Psicologia, formação de psicólogos e a escola: desafios contemporâneos Psicología, formación de psicólogos y la escuela: desafíos contemporáneos Psychology, professional preparation of the psychologist and the school: contemporary challenges

open access: yesPsicologia em Estudo, 2011
A atuação do psicólogo na educação cresce nos últimos anos, em instituições educativas e no atendimento à queixa escolar, mas ainda é comum, em diversos cursos de graduação, psicólogos se formarem sem ter tido contato direto com uma escola.
Flávia da Silva Ferreira Asbahr   +2 more
doaj   +1 more source

Estimating the Academic Performance of Secondary Education Mathematics Students: A Gain Lift Predictive Model

open access: yesMathematics, 2020
Several socioeconomic, environmental, ethnic, family, and educational factors influence an individual’s academic performance and can determine their school performance in mathematics.
Juan-Manuel Trujillo-Torres   +4 more
doaj   +1 more source

Predicting Success, Preventing Failure: An Investigation of the California High School Exit Exam [PDF]

open access: yes, 2008
Examines early indicators that identify fourth-grade students in San Diego who are at risk of failing the California High School Exit Exam, discusses implications for when and how to intervene to address those factors, and makes policy ...
Andrew C. Zau, Julian R. Betts
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

The Cost of Grade Retention [PDF]

open access: yes
This paper uses administrative longitudinal micro data on the universe of Junior High school students in Uruguay to measure the effect of grade failure on students' subsequent school outcomes.
Marco Manacorda
core  

Thoughts of Leaving: An Exploration of Why New York City Middle School Teachers Consider Leaving Their Classrooms [PDF]

open access: yes, 2012
This report explores the conditions under which middle-school teachers in New York City leave their schools, and the consequences of this turnover. The focus on middle schools stems from the widely-held view that the middle grades are a critical turning ...
Aaron M. Pallas, Clare K. Buckley
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

School Failure and Intergenerational “Human Capital” Transmission in Portugal [PDF]

open access: yes
School Failure and Intergenerational Human Capital Transmission… ABSTRACT A new education reform is about to be passed into Law, in Portugal, the extension of compulsory education until the 12th grade being one of the main goals.
Chagas Lopes, Margarida, Medeiros, João
core   +1 more source

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