Results 51 to 60 of about 9,509,571 (286)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
National School Feeding Program (PNAE): a conceptual model of barriers to acquiring family farming food items [PDF]
Ciência Rural: The National School Feeding Program (PNAE) is the oldest and most extensive food and nutrition program in Brazil. Art. 14 of Law 11.947 stipulate that at least 30% of its operational resources need be used to purchase family farming products.
Leandro Gomes de Oliveira +3 more
doaj +1 more source
The Feeding of School Children. [PDF]
The Economic Journal, 1915 n ...
Greenwood, Arthur, Bulkley, M. E.
openaire +1 more source
School Feeding Programme Menus and Protocols [PDF]
, 2023 The school feeding programme menus require the establishment of appropriate nutritional standards to guarantee a sufficient intake of calories, protein, carbohydrates, fats, vitamins, and minerals.
Belize. Ministry of Education, Culture, Science and Technology
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Desenvolvimento em Questão, 2016 In the global scenario, social and environmental problems are challenges that mobilize the searchfor alternatives to the current paradigm, such as social innovation and social technology.
Gabriel Borela Franzoni +1 more
doaj