Results 91 to 100 of about 16,003,623 (294)

Catalog: Boston University School of Medicine, School of Public Health [PDF]

, 1980
Viewbook/course catalog of the Boston University School of Public ...
Boston University School of Public Health
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Version 3.0 - laserbeamFoam: Laser ray-tracing and thermally induced state transition simulation toolkit

SoftwareX
This update to the growing laserbeamFoam toolbox introduces significant enhancements to the open-source simulation framework for laser–material interaction, enabling high-fidelity modelling of complex multiphysics phenomena.
Tom Flint, Petar Ćosić, Gowthaman Parivendhan, Simon A. Rodriguez, Ivan Bunaziv, Patrick O’Toole, Philip Cardiff   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Consent Form for Photography Paula Donohoe

, 2003
Consent form for Paula Donohoe's children's appearance in photos taken for the Modbury Hospital 30th ...
Modbury Hospital
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Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Consent Form for Photography Barbara Cheeseman

, 2003
Consent form from Barbara Cheeseman to appear in photographs from the 30th ...
Modbury Hospital
core  

Factors influencing vaccine hesitancy among United Kingdom adolescents in a senior high school environment and actions to address it

Human Vaccines & Immunotherapeutics
We explored adolescent viewpoints on vaccines and hesitancy using an anonymized, validated, self-completed electronic questionnaire amongst state-school Year 12–13 adolescents in London, UK. As the response rate was low (Cohort 1; n = 112/486, 23.0%), we
Francis Drobniewski, Marcia Ashmi, Raheelah Ahmad, Changchunzi He, Marianna Bogdanova, Alan Garbacz, Ahmed Moustafa   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source