Results 191 to 200 of about 7,693,545 (307)

Continuum of care in hospitalized patients with opioid or stimulant use disorder and infectious complications of drug use-substance use/infectious disease integrated clinic compared to treatment as usual to prevent infection-related readmission (CHOICE-STAR): a study protocol for an effectiveness-implementation randomized controlled trial. [PDF]

Trials
Rosenthal ES, Lavoie MC, Traver E, Gryczynski J, Nordeck C, Carpenter JE, Reece R, Kuo I, Catalanotti JS, Steck AR, Cooper G, Fujita AW, Murphy SM, Mansfield ME, Ramadhani HO, Silk R, Masur H, Kattakuzhy S.   +17 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Internet Addiction and Its Association with Depression, Anxiety and Quality of Life Among School-going Adolescents: A Cross-sectional Study. [PDF]

Ann Neurosci
Panghal A, Jeenger J, Sharma M, Mathur DM.   +3 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Prevalence and correlates of risky sexual behaviour among in-school adolescents in Bulawayo, Zimbabwe: a cross-sectional study. [PDF]

BMJ Public Health
Ndlovu R, Moyo PL.
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

16 to 19 school and academy sixth form allocation calculation toolkit: 2020 to 2021: A guide, January 2020 [PDF]

, 2020

core  

Food preparation skills and obesity risk in European children aged 6-9 years: a cross-sectional study using WHO COSI 2022-2024'. [PDF]

Eur J Nutr
Vaughan KL, Buoncristiano M, Williams J, Duleva V, Hejgaard T, Susovits K, Abdrakhmanova S, Petrauskiene A, Racu MV, Spiroski I, Hetherington MM, Cade JE.   +11 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Exploring Feature Priorities and User Needs in Developing Virtual Study Assistants. [PDF]

JMIR Form Res
Tsai CS, Lee H, Szewczyk W, Palmer JK, Putnam S, Munson SA, Heffner JL, Vasbinder A, Paullada A, Yuwen W, Reding KW.   +10 more
europepmc   +1 more source