Results 91 to 100 of about 4,859,482 (379)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann   +6 more
wiley   +1 more source

Juvenile substance use and effects of substance use disorder on incarceration and grade retention in a sample referred for court clinic mental health evaluation [PDF]

open access: yes, 2015
A significant amount of adolescents are involved in the drug court system. Within a few of the systems are mental health clinics providing more specific services to youth introduced into the courts.
Oliveira, Cassandra
core   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan   +12 more
wiley   +1 more source

Early years : subject profile (SPICe briefing; 11/51) [PDF]

open access: yes, 2011
"This subject profile provides an introduction to services for pre-school children. It updates and expands SB 06/83 published in October 2006. Early Years refers to pre-school education, child health, children‟s social work and childcare.
Kidner, Camilla
core  

The views of parents concerning the planning of services for rehabilitation of families of children with congenital cardiac disease [PDF]

open access: yes, 2003
Background and purpose: Although much previous research has focused on the medical aspects of congenital cardiac disease, there is a growing body of research which suggests that families may need help and support with the wider issues associated with the
Kendall, L   +3 more
core   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster   +11 more
wiley   +1 more source

More Than a Place to Sleep: Understanding the Health and Well-Being of Homeless High School Students [PDF]

open access: yes, 2017
In New York City, one out of every eight public school students has been homeless at some point in the past five years. One in four (26%) of these students is in high school.

core  

Evaluating service supply in conditional cash transfers [PDF]

open access: yes, 2015
textConditional cash transfers are poverty reduction mechanisms that seek to increase demand of social services by combining an income effect with a health or education requirement. This demand-side strategy relies on a tacit assumption about the quality
Sabat Pereyra, Nadia Melina
core   +1 more source

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