Results 71 to 80 of about 968,288 (254)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Nursing Practice and Telehealth in School Health Services: A Scoping Review. [PDF]

Healthcare (Basel), 2023
Ayuso Margañon R, Llistosella M, Ayuso Margañon S, Rojano Navarro M, Bou Gràcia N, Sillero Sillero A.   +5 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Effectiveness of Health Education on Nutrition and Hygiene Among School-going Adolescents in Hyderabad, India: A Pre- and Post-interventional Study

Preventive Medicine: Research & Reviews
Introduction: Malnutrition and inadequate hygiene are major public health challenges globally. The current study assessed the effectiveness of nutrition and hygiene education among school-going adolescents in Hyderabad, Telangana.
Avula Harish Sagar, Adelli Srividya, G. Alekhya, Erugadinla Vennela, Aluka Saitejaswi   +4 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Guideline evaluation and implementation mechanisms in school health services (GuideMe): protocol for a hybrid randomized factorial trial. [PDF]

BMC Health Serv Res, 2023
Sagatun Å, Engell T, Brekke M, Sjølie H, Ekornes SM, Waldum-Grevboe KS, Pape K, Kvaløy K, Jeneson A, Trøan AS, Askeland AL, Stien L, Holen S.   +12 more
europepmc   +1 more source

Development and feasibility study of a Culturally Tailored Asthma intervention using a mixed-method approach at the primary school level in Malaysia: Challenged by the COVID-19 pandemic [PDF]

Malaysian Family Physician
Introduction: The World Health Organization recommends incorporating asthma programmes into national school health services, although this recommendation is rarely implemented.
Siti Nurkamilla Ramdzan, Ee Ming Khoo, Steve Cunningham, Jayakayatri Jeevajothi Nathan, Nursyuhada Sukri, Hilary Pinnock   +5 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

School Health Services and Health Education Curricula in Greece: Scoping Review and Policy Plan. [PDF]

Healthcare (Basel), 2023
Soultatou P, Vardaros S, Bagos PG.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source