Directed Evolution of T7 RNA Polymerase Minimizes dsRNA By-product and Enables High-Fidelity mRNA Synthesis for Demanding Therapeutic Applications. [PDF]
Qin W +6 more
europepmc +1 more source
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen +12 more
wiley +1 more source
Toward the Chemoenzymatic Synthesis of DNA-Encoded Libraries. [PDF]
Schaub D +5 more
europepmc +1 more source
Uchimata: a toolkit for visualization of 3D genome structures on the web and in computational notebooks. [PDF]
Kouřil D +3 more
europepmc +1 more source
De novo identification of the specificities of recurrently identified human T cell receptors. [PDF]
Kasbe M +7 more
europepmc +1 more source
Draft genome sequences of <i>Alicyclobacillus</i> strains isolated from the Chinoike-Jigoku hot spring, Oita, Japan. [PDF]
Sato Y, Miyamoto E, Sato Y, Maeno S.
europepmc +1 more source
Limited effect of short- to mid-term storage conditions on an Australian farmland soil RNA virome. [PDF]
Sadiq S +7 more
europepmc +1 more source
mTACT: A cell type-specific transportome-scale amiRNA toolbox to overcome functional redundancy in Arabidopsis. [PDF]
Anfang M +14 more
europepmc +1 more source

