Results 31 to 40 of about 202,153 (252)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
An Investigation and Comparison of High-School Teachers and Students of Ahvaz Viewpoints on the Necessity of School Libraries and Librarians [PDF]
تحقیقات اطلاعرسانی و کتابخانههای عمومی, 2017 Purpose: The purpose of the research is to compare the viewpoints of Ahvaz high-school teachers and students about the necessity of existence of school libraries and professional librarians, to determine the position of libraries in the education system.
Zahed Bigdeli, Leila Zolfaghari asl
doaj
Dormitory libraries: libraries in dormitories
Knjižnica, 2004 Dormitory libries are not justly treated in Slovenia. They have a double purpose: to develop student literacy, especially reading, critical and creative competence and, moreover, to provide students with opportunities for learning and active spending of ...
Peter Pavletič
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Frontiers in EducationIntroductionAlthough literature shows that libraries can play a significant role in student learning, very little is known about how the availability of libraries can transform rural education ecosystems.
Lulama Mdodana-Zide, Godsend T. Chimbi
doaj +1 more source
School libraries, political information and information literacy provision:
Journal of Information Literacy, 2016 This paper presents the findings of research which explored Scottish school libraries’ information provision and information literacy (IL) support in the run-up to two major political events: the 2014 Scottish Independence Referendum (SIR) and the 2015 ...
Lauren Smith
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Revista Interamericana de Bibliotecología, 2017 This study conducted a review of government initiatives and projects aimed at strengthening school libraries in the country, with special emphasis in the city of Medellin, from the 19th century to the second decade of the 21st century.
Sandra Patricia Bedoya Mazo
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source