Results 121 to 130 of about 18,879,441 (355)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Cracking the Code of Cyberbullying Effects: The Spectator Sports Solution for Emotion Management and Well-Being Among Economically Disadvantaged Adolescents

Behavioral Sciences
This study explores the relationships among cyberbullying, emotion management, and well-being, with a focus on economically disadvantaged students. Employing a reflective factor model, we disentangle emotion management into four dimensions and explore ...
Ilrang Lee, Yonghwan Chang, Taewoong Yoo, Emily Plunkett   +3 more
doaj   +1 more source

Private school enrollment and public school performance

Public Choice, 1993
Federal, state, and local expenditures for public education amounted to $184 billion, or $4,538 per pupil, in 1987-88 (Lieberman, 1989: 29). At the same time, educational achievement in the United States, whether measured in terms of student performance on standardized tests, literacy rates, or other dimensions of learning, has been stagnant for a ...
Shughart, William F., II, Couch, Jim F., Williams, Al L.   +2 more
openaire   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

School performance management practices and school achievement

International Journal of Productivity and Performance Management, 2012
PurposeThe literature is very rich in its discussion on how to measure school performance, but there are still a number of gaps to investigate in relation to the determinants of that performance, especially at the level of school performance management practices.
Sarrico, Cláudia S., Rosa, Maria J., Manatos, Maria J.   +2 more
openaire   +2 more sources

Reading on Grade Level in Third Grade: How Is It Related to High School Performance and College Enrollment? [PDF]

, 2010
Illustrates how third-grade reading level correlates with eighth-grade reading level, which, along with ninth-grade school traits, correlates with ninth-grade performance, which in turn correlates with high school graduation and college attendance ...
Cheryl Smithgall, Joy Lesnick, Julia Gwynne, Robert M. Goerge   +3 more
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The Relationship Between Students’ ICT Use and Their School Performance: Evidence from PISA 2015 in the Czech Republic

Orbis Scholae, 2019
In the last decades, Information and Communication Technologies (ICT) have become recognized as an important and integral part of life as well as education.
Libor Juhaňák, Jiří Zounek, Klára Záleská, Ondřej Bárta, Kristýna Vlčková   +4 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Adherence to pharmacotherapy improves school performance in children with rhinitis and asthma

Revista Alergia México, 2018
Background: Adherence to pharmacotherapy reduces clinical symptoms of asthma and rhinitis, however, little is known of its impact on school performance in children.
Jorge Mario Sánchez, Andrés Sánchez, Ricardo Cardona   +2 more
doaj