Results 161 to 170 of about 431,491 (260)
Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease
Annals of Neurology, EarlyView.Objective
Accurate electrode placement and individual stimulation parameters influence the outcomes of subthalamic deep brain stimulation in Parkinson's disease. Neuroimaging‐based models can help evaluate how electrode placement impacts improvement, aiming to reduce the burden of programming.Patricia Zvarova, Christina van der Linden, Ningfei Li, Konstantin Butenko, Thea Berger, Garance M. Meyer, Ilkem Aysu Sahin, Lukas L. Goede, Bahne H. Bahners, Barbara Hollunder, Till A. Dembek, Andrew R. Pines, Martin Reich, Jens Volkmann, Vincent J. J. Odekerken, Rob M. A. de Bie, Xin Xu, Zhipei Ling, Chen Yao, Andrea A. Kühn, Surjo R. Soekadar, Kerstin Ritter, Michael T. Barbe, Veerle Visser‐Vandewalle, Michael D. Fox, Jan Niklas Petry‐Schmelzer, Nanditha Rajamani, Andreas Horn +27 morewiley +1 more sourceUse of Machine Learning to Identify Markers of Risk for Fragile X‐Associated Tremor/Ataxia Syndrome: A Preliminary Analysis
Annals of Neurology, EarlyView.Objective
The objective of this study was to examine whether machine learning has the capacity to prospectively identify and predict the emergence of Fragile X‐associated tremor/ataxia syndrome (FXTAS) among male fragile X premutation carriers (PCs). Methods
We explored neuropsychological and motor evaluation metrics, brain magnetic resonance imaging ...Chitrabhanu Gupta, Angeela Poudel, Jun Yi Wang, Randi Hagerman, Glenda Espinal, Jessica Famula, Andrea Schneider, Flora Tassone, Susan M. Rivera, Chen‐Nee Chuah, David Hessl +10 morewiley +1 more sourceMonoallelic POLR3A Variants Cause Early‐Onset Peripheral Neuropathy
Annals of Neurology, EarlyView.Objective
Biallelic variants in genes encoding the RNA polymerase III complex (Pol III) cause a spectrum of neurological disorders primarily affecting the central nervous system. Monoallelic variants have been reported in the POLR3B subunit only, associated with neurodevelopmental disorder, epilepsy, and peripheral neuropathy.Luiza L. P. Ramos, Jevin M. Parmar, Robin Wijngaard, Bianca R. Grosz, Tamas Lazar, Ligia Mateiu, Steve Vucic, Kishore R. Kumar, Dennis Yeow, Laura I. Rudaks, Lonneke de Boer, Annemarie de Vreugd, David A. Koolen, Thatjana Gardeitchik, Anita Cairns, Krishnan Iyengar, Fernando Kok, Fernanda Barbosa Figueiredo, Alzira Alves de Siqueira Carvalho, Luiz S. Mageste Barbosa, Rodrigo Rezende Arantes, Tyler Rehbein, Jordan E. Bontrager, Elizabeth P. Wood, Janet E. Sowden, Gavin Monahan, Meutia Kumaheri, Ivy Cuijt, Melina Ellis, Gonzalo Perez‐Siles, Elyshia McNamara, Ronald van Beek, Celine B. Meijers, Ivaylo Tournev, Stephan Zuchner, Shoshana J. Wodak, Clara D. M. van Karnebeek, Nigel Laing, Liana N. Semcesen, David A. Stroud, David N. Herrmann, Velina Guergueltcheva, Marina L. Kennerson, Machteld M. Oud, Gianina Ravenscroft, Ayse Candayan, Albena Jordanova +46 morewiley +1 more sourceA next generation of the schema therapy model of personality pathology: A cross-cultural and international study protocol. [PDF]
PLoS OneMamali FC, Rijkeboer M, Molenaar D, Rameckers SA, Panzeri M, Arntz A, Lee CW, Brockman R, Ho Tan D, Mozumder MK, Gayen TK, Dyakov D, Stabrouskaya Y, Gatam A, Lobanovich V, Kanavina S, Romanovich V, Andreevich OA, Tkhoryk N, Shabaikovich A, Dierckx E, Pauwels E, Eggermont K, Matos FR, Puléo Barela R, Frossard LQ, Lazarova IS, Peneva K, Katrandjieva A, St Lazarova A, Zhu Y, Lyu B, Liu Y, Li L, Qin H, Guo X, Hu X, Zhang S, Ma OYT, Tang ALY, Moeller SB, Arendt ITP, Bach B, Meline J, Tapia G, M'bailara K, Abdushelishvili K, Begiashvili A, Badrishvili N, Gvinianidze A, Akopashvili L, Khabazi I, Kopf-Beck J, Leithne C, Renner F, Egli S, Quaatz SM, Malogiannis IA, Giannoulis E, Simos G, Unoka Z, Simon L, Simon V, Munivenkatappa M, Sudhir PM, Kohli TK, Shrivastava A, Misra AA, Khanna A, Louis JP, Santoso NM, Shanti TI, Witarso LS, Hedayati M, Samimi A, Malekasgar S, Basile B, Krone I, Orupe A, Gecaite-Stonciene J, Pociunaite J, Renee Tan HJ, Chan E, Heimkumar V, Kadri N, Karroumi S, Chentaf FZ, Ezzahiri N, Rachidi H, Bouchebti S, Bouidar H, Hikmat W, Chroukate F, Ennaciri Z, Thimm JC, Lorentzen V, Michałowski JM, Popiel AE, Mącik D, Browarczyk WM, Céu Salvador MD, Păduraru AE, Semeniuc SE, Stroian PI, Șubredu I, Yaltonskaya A, Maryasova D, Titova O, Gegel N, Gorodentseva N, Skryabina M, Plichko A, Pavlova O, Prokaeva S, Malashchanka V, Michelle Neo HL, Stein DJ, Hawa W, Hartmann JP, Lee E, Song Y, Gómez-Juanes R, Calvete E, Cid J, Schmidt RE, Homan S, Sakulsriprasert C, Phukao D, Thawornwutichat R, Mamoon W, Chandraungs A, Supreeyaporn N, Bachrach N, Keulen-de Vos M, Lobbestael J, Dorrestijn E, Krans J, Yakin D, Baştak D, Taşlioğlu Sayiner AC, İnce B, Tasilaridis S, Ergelen M, Kennedy FC, Taylor CDJ, First MB, Lockwood G, Appenzeller Z, Norton AR, Seeley-Wait E, Abbott MJ, Allen KL, Hasan S, Morales Hernández SA, Sharaf AM, Ruths FA. +155 moreeuropepmc +1 more sourceBehavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial
Arthritis &Rheumatology, EarlyView.Objective
The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods
This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.Joshua F. Baker, Katherine D. Wysham, Mercedes Quinones, Bryant R. England, Kaitian Jin, Marianna Olave, Sarah Wetzel, Rachel L. Gillcrist, Criswell Lavery, Natalie Keller, Bridget Kramer, Bibianna Ateh, Hannah Brubeck, Daniel K. White, Alexis Ogdie, Rui Xiao, Tuhina Neogi, Carla R. Scanzello +17 morewiley +1 more source