Results 251 to 260 of about 7,434,491 (411)

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

Metabolic syndrome prevalence and cardiovascular disease risk among school teachers. [PDF]

open access: yesInt J Occup Med Environ Health
Ramadan MA, Saif Eldeen AS, Mourad BH.
europepmc   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

open access: yesAdvanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das   +13 more
wiley   +1 more source

Piezo‐Phototronic PVDF/HfO2/Nano‐Cu Heterostructured Thin Film for Flexible Self‐Powered Multimodal Sensing

open access: yesAdvanced Science, EarlyView.
Electrospinning a composite of PVDF, HfO2, and nano‐Cu transforms the discrete precursors into a continuous nanofiber mesh, forming a multi‐interface heterostructure with embedded nanoparticles. The presence of HfO2 and nano‐Cu at the fiber interfaces induces a highly aligned β‐phase, which enhances piezoelectric crystallinity and improves the material'
Jiawei Gu   +9 more
wiley   +1 more source

A Wearable System Featuring Biomimetic Spatially Distributed Iontronic Sensing Array for Dynamic Monitoring of Deep Tissue Modulus

open access: yesAdvanced Science, EarlyView.
A fully wearable system enables real‐time, dynamic, and accurate monitoring of Young's modulus in multilayer tissues containing deep muscle. It demonstrates high accuracy and robustness across simulations, benchtop validations, and human testing. It quantifies edema severity and tracks muscle stiffness during rest, loaded elbow flexion, rope skipping ...
Zhenning Wang   +12 more
wiley   +1 more source

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