Results 31 to 40 of about 134,004 (257)

Satisfaction with the School Environment and Involvement in Peer Violence and Cyberbullying in Croatian Vocational High School [PDF]

Interdisciplinary Description of Complex Systems
Peer violence is a widespread phenomenon with focus of experts and prevention programs. Participating in peer violence and violence on the Internet can seriously damage a child’s well-being and mental health and leave long-term consequences.
Ivan Pakšić, Roberta Matković, Lucija Vejmelka   +2 more
doaj   +1 more source

Prevalence of Violence among High School Students in Hat Yai Municipality, Southern Thailand: ICAST-CI Thai Version Study

Journal of Health Science and Medical Research (JHSMR), 2018
Objective: To determine the prevalence and risk factors of school violence among Thai high school students using a Thai version of the International Society for the Prevention of Child Abuse and Neglect (ISPCAN) Child Abuse Screening Tool-Children ...
Sasivara Boonrusmee, Tansit Saengkaew, Nannapat Pruphetkaew, Somchit Jaruratanasirikul   +3 more
doaj   +1 more source

A stepped-wedge randomized trial investigating the effect of the Leadership and Organizational Change for Implementation (LOCI) intervention on implementation and transformational leadership, and implementation climate

BMC Health Services Research, 2022
Background This study evaluates the Leadership and Organizational Change for Implementation (LOCI) strategy and its effect on implementation leadership, transformational leadership, and implementation climate.
Ane-Marthe Solheim Skar, Nora Braathu, Nadina Peters, Harald Bækkelund, Mathilde Endsjø, Aida Babaii, Randi Hovden Borge, Tore Wentzel-Larsen, Mark G. Ehrhart, Marisa Sklar, C. Hendricks Brown, Gregory A. Aarons, Karina M. Egeland   +12 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Firearm injury hospitalizations and handgun purchaser licensing laws: longitudinal evaluation of state-level purchaser licensure requirements on firearm violence, 2000–2016

Injury Epidemiology
Background Handgun purchaser licensing (HPL) laws mandate individuals to obtain a license from law enforcement before buying a firearm. Research indicates these laws effectively reduce various forms of fatal firearm violence, including homicides ...
Mitchell L. Doucette, Nicholas S. Meyerson, Cassandra K. Crifasi, Elizabeth Wagner, Daniel W. Webster   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Predicting neighborhood-level violence from features of the physical and social environment with machine learning

Injury Epidemiology
Background Violence is a leading cause of death and disparity in the United States. Individuals’ physical and social environments can prevent or foster violence, but these complex milieus are challenging to model.
Veronica A. Pear, Colette Smirniotis, Rose M. C. Kagawa   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source