Results 91 to 100 of about 262,428 (261)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Nonmarket outcomes of schooling [PDF]
Most studies of the benefits of education focus on market outcomes, particularly labor market returns. But the rewards of education are not limited to success at finding a job and earning money; schooling also affects nonmarket outcomes, such as one's ...
S. Zuvekas, B. Wolfe
core
Is schooling good for the development of society? The case of South Africa
South African Journal of Education, 2011 This paper is concerned with three possible theoretical relationships, between education and social, economic and political development, that - (a) education improves society, (b) education reproduces society as it is and (c) education actually makes ...
Clive Harber, Vusi Mncube
doaj +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Impact of Schooling on the Timing of Marriage and Fertility: Evidence from a Change in Compulsory Schooling Law [PDF]
This paper estimates the impact of schooling on the timing of marriage and early fertility using the 2003 Turkish Demographic and Health Survey and duration analysis methodology.
Kirdar, Murat G. +2 more
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FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Fertility shock and schooling [PDF]
This paper uses Demographic and Health Surveys data from about 30 sub-Saharan African countries to investigate the link between the birth of an ?unintended child? and schooling decisions of children (dropout and entry).
KOISSY KPEIN Sandrine Aïda +2 more
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, 1998 There has been no previous systematic exploration of the childhood experiences of Special Hospital patients. This study examined the family background, separations and disruptive incidents, which constituted a loss, of 208 patients who had been admitted ...
Schooling, Jean
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source