Results 71 to 80 of about 262,428 (261)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Competing interests? NAPLAN and middle schooling assessment practices

open access: yes, 2013
In Australia, the introduction of the National Assessment Program for Literacy and Numeracy (NAPLAN) in 2008 marked a national shift towards an accountability driven education agenda.
Swain, Katharine, Pendergast, Donna
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Schooling Quality and Economic Growth [PDF]

open access: yes
Many studies of the determinants of economic growth rates across countries use a measure of schooling quantity, such as mean secondary school enrolment rates, to proxy for the rate of human capital accumulation.
Neri, F.
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The Causal Effect of Parents' Schooling on Children's Schooling - A Comparison of Estimation Methods [PDF]

open access: yes
We review the empirical literature that estimates the causal effect of parent’s schooling on child’s schooling, and conclude that estimates differ across studies.
Mikael Lindahl   +2 more
core  

Una aproximación a la historia de la escolarización de las gitanas y gitanos españoles (1º parte: siglos XV-XIX). An approach to the history of schooling of Spanish gypsies (part 1: centuries XV-XIX)

open access: yesCabás, 2015
(ES) Si poca atención y publicaciones se han prestado al tema de la historia de los gitanos españoles, menos aún a la historia de su escolarización y educación en estos seis siglos de conciudadanía accidentada.
Jesús Salinas Catalá
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Forced to Be Rich? Returns to Compulsory Schooling in Britain [PDF]

open access: yes
Do students benefit from compulsory schooling? Researchers using changes in compulsory schooling laws as instruments have typically estimated very high returns to additional schooling that are greater than the corresponding OLS estimates and concluded ...
Hart, Robert A., Devereux, Paul
core   +2 more sources

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