Results 81 to 90 of about 778,611 (294)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Navigating education and parenthood: Teenage mothers' support systems in Namibia's Omusati region [PDF]

Journal of Studies in Social Sciences and Humanities
This research explored the experiences of teenage mothers enrolled in schools in the Omusati region of Namibia. The study examines how they perceive and navigate the support systems available to them in their ecological context.
Dr. Rauha Haipinge, Dr. Halima Namakula*
doaj  

School Pharmacist/School Environmental Hygienic Activities at School Site

YAKUGAKU ZASSHI, 2016
The "School Health and Safety Act" was enforced in April 2009 in Japan, and "school environmental health standards" were established by the Minister of Education, Culture, Sports, Science and Technology. In Article 24 of the Enforcement Regulations, the duties of the school pharmacist have been clarified; school pharmacists have charged with promoting ...
openaire   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Immigrants' return to schooling in Sweden [PDF]

The aim of this paper is to examine if the returns to immigrants’ schooling are lower than the returns to natives’ schooling. In addition the paper tries to establish whether immigrants who invest in different amounts of Swedish education also differ in ...
Nordin, Martin
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Une enquête ethnographique en centre d’hébergement : démarches collaboratives et implications réciproques du chercheur et des professionnels.

Sociétés et Jeunesses en Difficulté, 2016
From an ethnographical investigation conducted as part of an answer to the ONED's call for tenders in 2012, this article proposes to analyse the relationship maintained between the researcher and a socio-educational team whose educational work undertaken
Delphine Bruggeman
doaj  

What Determines Adult Cognitive Skills? Impacts of Pre-Schooling, Schooling and Post-Schooling Experiences in Guatemala [PDF]

Most investigations of the importance of and the determinants of adult cognitive skills assume that (a) they are produced primarily by schooling and (b) schooling is statistically predetermined.
Aryeh D. Stein, Emory University, Emily L. Behrman, Erica Soler-Hampejsek, Jere R. Behrman, University of Pennsylvania, John Hoddinott, John Maluccio, Manuel Ramirez-Zea, Institute of Nutrition for Central America and Panama, Reynaldo Martorell   +7 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Proceedings of the Conference on Human and Economic Resources [PDF]

A number of papers .nd that changes in schooling are not correlated with changes in per capita income. Two non-competing interpretations that have been given are that the social return on schooling is close to zero and the measurement error of changes in
Marcelo Soto
core