Results 61 to 70 of about 8,655,714 (345)
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Include medical ethics in the Research Excellence Framework [PDF]
, 2011 The Research Excellence Framework of the Higher Education Funding Council for England is taking place in 2013, its three key elements being outputs (65% of the profile), impact (20%), and “quality of the research environment” (15%).
Boyd, K +5 more
core +2 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
A medical school in Zambia [PDF]
Journal of Public Health, 1997 The Medical School in Zambia was founded in 1968, some four years after independence. The first graduates qualified in 1973, and over the intervening 23 years there have been some 700 medical graduates, 600 of them Zambian.These doctors are now working all over the world, and the standard of their training compares favourably with that at medical ...
openaire +2 more sources
CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Scientific Reports, 2022 Monoclonal antibodies (MAb) to members of the Small Ubiquitin-like modifier (SUMO) family are essential tools in the study of cellular SUMOylation. However, many anti-SUMO MAbs are poorly validated, and antibody matching to detection format is without an
Alexander J. Garvin +2 more
doaj +1 more source
Systematic review of pain medicine content, teaching, and assessment in medical school curricula internationally [PDF]
, 2018 Introduction: Pain management is a major health care challenge in terms of the significant prevalence of pain and the negative consequences of poor management.
Bate, Frank +5 more
core +3 more sources
Bedside ultrasound education in Canadian medical schools: A national survey
Canadian Medical Education Journal, 2016 Background This study was carried out to determine the extent and characteristics of bedside ultrasound teaching in medical schools across Canada. Methods A cross-sectional, survey-based study was used to assess undergraduate bedside ultrasound education
Peter Steinmetz +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
What can medical schools do to help recruit future GPs? [PDF]
, 2016 No abstract ...
Morrison, Jill
core +1 more source