Results 81 to 90 of about 1,452,335 (308)

Factors affecting the concentrations of heavy metals in precipitation of Tehran using factor analysis method

سلامت و محیط, 2016
Backgrounds and Objectives: Quantity of trace metals in the wet precipitation can illustrate the environmental pollution of different urban areas. Up to now, there is no study regarding the chemistry of wet precipitation in Tehran .The objectives of this
H Kamani, M Hoseini, G.H Safari, A.H Mahvi, H Zarei   +4 more
doaj  

Plasma biomarkers are associated with agitation and regional brain atrophy in Alzheimer’s disease

Scientific Reports, 2017
This study investigated the relationships among plasma biomarkers, regional brain atrophy, and clinical symptoms in patients with Alzheimer’s disease (AD; n = 177), mild cognitive impairment (MCI; N = 60) and controls (n = 108).
Jung-Lung Hsu, Wei-Ju Lee, Yi-Chu Liao, Jiing-Feng Lirng, Shuu-Jiun Wang, Jong-Ling Fuh   +5 more
doaj   +1 more source

Physical activity and the prevention, reduction, and treatment of alcohol and/or substance use across the lifespan (The PHASE review): protocol for a systematic review

Systematic Reviews, 2018
Background Alcohol and substance use results in significant human and economic cost globally and is associated with economic costs of £21 billion and £15billion within the UK, respectively, and trends for use are not improving.
Tom P. Thompson, Adrian H. Taylor, Amanda Wanner, Kerryn Husk, Yinghui Wei, Siobhan Creanor, Rebecca Kandiyali, Jo Neale, Julia Sinclair, Mona Nasser, Gary Wallace   +10 more
doaj   +1 more source

End-of-Life Issues in UK Medical Schools [PDF]

, 2015
Objective: A descriptive study to determine the current status of end-of-life (EOL) issues in UK medical schools.Methods: A brief questionnaire was mailed to the 31 medical schools in the United Kingdom in the spring of 2013.
Dickinson, George, Paul, Liz
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Medical education and the pursuit of excellence : the quest for the Holy Grail? [PDF]

, 2008
Medical education in Europe is currently facing enormous challenges brought about by the number and the diversity of medical schools that are now within the fold.
Vassallo, Josanne
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Erectile dysfunction and associated factors among patients with diabetes in Public hospitals of Harari region, Eastern Ethiopia: modified poisson regression model

BMC Endocrine Disorders
Background Erectile dysfunction is a common problem among patients with diabetes, often going undiagnosed and having a significant negative impact on their health. This condition necessitates accurate evaluation and early intervention.
Abebe Seyoum, Aboma Motuma, Behailu Hawulte, Tamirat Getachew, Adera Debella, Addis Eyeberu   +5 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Influence of national culture on the adoption of integrated medical curricula [PDF]

, 2010
Integrated curricula have been implemented in medical schools all over the world. However, among countries different relative numbers of schools with integrated curricula are found.
Mariëlle Jippes, Gerard D. Majoor
core   +1 more source