Results 111 to 120 of about 1,653,373 (168)

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

The FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti, Andre Schutzer Godoy, Caio Cesar Mello Capetti, Rafaela Sachetto Fernandes, Vanessa O. A. Pellegrini, Ornella M. Ontañon, Eleonora Campos, Rodrigo V. Portugal, Igor Polikarpov   +8 more
wiley   +1 more source

Blocking protein quality control degradation leads to structural stabilization of DHFR indel variants

The FEBS Journal, EarlyView.
Blocking protein quality control degradation by deleting the E3 ligases Ubr1 or San1 stabilizes many DHFR insertion and deletion variants that are otherwise partially unfolded. These hypomorphic variants regain folding at lower temperatures or upon methotrexate binding, revealing that PQC degradation can remove proteins that are still functionally ...
Sven Larsen‐Ledet, Caroline H. Suhr, Sarah Gersing, Celeste M. Hackney, Amelie Stein, Kaare Teilum, Rasmus Hartmann‐Petersen   +6 more
wiley   +1 more source

Lignan‐rich Norway spruce (Picea abies) resin extract exhibits anti‐inflammatory, skin‐regenerative and anti‐acne effects: In vitro, in silico, biocompatibility and exploratory clinical findings

International Journal of Cosmetic Science, EarlyView.
GA text A 30% Picea abies resin extract cream combined antimicrobial, anti‐inflammatory and early pro‐repair activities relevant to acne‐prone skin. The formulation showed strong activity against Cutibacterium acnes, reduced inflammatory cytokines and demonstrated promising tolerability and efficacy in an exploratory in‐use study. Abstract Objective To
Simone Parrotta, Kamilla Yamileva, Laura Punakallio, Maryam Ghanbarirad, Evgen Multia   +4 more
wiley   +1 more source

Demo video of Schrödinger\u27s box: "nails"

Demo video of Schrödinger\u27s box ...
Weger, Marian (University of Music and Performing Arts Graz, Austria)
core  

HvPHO1 Controls a Glucose 1‐Phosphate–SnRK1 Signalling Module That Coordinates Starch Accumulation in Barley Endosperm

Plant Biotechnology Journal, EarlyView.
ABSTRACT Developing barley grains must balance the use of imported sucrose between soluble sugars and storage starch, but how this balance is controlled remains unclear. Here we show that loss of the plastidial α‐glucan phosphorylase HvPHO1 causes starch and soluble sugars to accumulate concurrently in barley grains.
Yulong Li, Yujia Chen, Jing Liu, Ping Yang, Guangqi Gao, Carlos Guzmán, Qiang Xu, Yazhou Zhang, Yanlin Liu, Pengfei Qi, Mei Deng, Shoufen Dai, Jian Ma, Guoyue Chen, Jirui Wang, Youliang Zheng, Yuming Wei, Qiantao Jiang   +17 more
wiley   +1 more source

Demo video of Schrödinger\u27s box: "scrub"

Demo video of Schrödinger\u27s box ...
Weger, Marian (University of Music and Performing Arts Graz, Austria)
core  

Radial canonical AdS3 gravity and T T ¯ $$ T\overline{T} $$

Journal of High Energy Physics
We employ an ADM deparametrization strategy to discuss the radial canonical formalism of asymptotically AdS3 gravity. It leads to the identification of a radial ‘time’ before quantization, which is the volume time, canonically conjugate to York time ...
Matthew J. Blacker, Nele Callebaut, Blanca Hergueta, Sirui Ning   +3 more
doaj   +1 more source

Energy-Conserving Explicit Relaxed Runge–Kutta Methods for the Fractional Nonlinear Schrödinger Equation Based on Scalar Auxiliary Variable Approach

Axioms
In this paper, we present a novel explicit structure-preserving numerical method for solving nonlinear space-fractional Schrödinger equations based on the concept of the scalar auxiliary variable approach.
Yizhuo Zhao, Yu Li, Jiaxin Zhu, Yang Cao
doaj   +1 more source

Probing the molecular determinants of emission enhancement in RNA aptamer–metal complex systems

Photochemistry and Photobiology, EarlyView.
Light up aptamer: fluorophore pairs are widely used in sensing and imaging, with coordination complex fluorophores providing specific benefits due to their long‐lived emission. Here, we examined key structural and electronic features of these metal complexes to identify the requirements for productive engagement with an RNA aptamer.
Sarah M. Kriger, Joseph Spiconardi, Nathan Ennist, Edith C. Glazer   +3 more
wiley   +1 more source

Demo video of Schrödinger\u27s box: "cat"

Demo video of Schrödinger\u27s box ...
Weger, Marian (University of Music and Performing Arts Graz, Austria)
core