Quantifying the Nonclassicality of the Kirkwood-Dirac Quasiprobability Distribution Under Discrete-Time Dynamics. [PDF]
Ding Z, Zhou SQ.
europepmc +1 more source
We report the synthesis of 21 novel thiazolidinedione–pyrazolopyrimidinone derivatives (12a–u), prepared by coupling thiazolidinedione and pyrazolopyrimidinone pharmacophores through various alkyl linkers. The compounds were characterized spectroscopically and evaluated against the Mtb H37Rv strain, identifying compounds 5c and 5d as potent ...
Pule Seboletswe +8 more
wiley +1 more source
Anomalous Behavior Induced by a Single Impurity in Non-Hermitian Topological Systems with Nonreciprocal Coupling. [PDF]
Wang J, Wang Z, Ma X, Yi X.
europepmc +1 more source
Prospects of Quantum Computing
ABSTRACT It has been anticipated that quantum computing (QC) would solve computational tasks involving quantum phenomena intractable for supercomputers based on digital technology. Concurrently, however, the vast development of artificial intelligence (AI) has resulted in systems targeting these real‐world problems with unprecedented progress including
Shili Zhang +3 more
wiley +1 more source
Energy and thermal magnetization of diatomic molecules under the enhanced Pöschl-Teller potential. [PDF]
Eyube ES +4 more
europepmc +1 more source
Peptide binding at the gasdermin D exosite reveals the structural basis for targeting the site
We describe the first structure of gasdermin D with a putative caspase inhibitor peptide analog at 1.6 Å resolution. This work suggests potential druggability of gasdermin D at the exosite by leveraging structure‐based computational design with biochemical characterization.Gasdermin D (GSDMD) has been identified as a critical component of the ...
Renjing Wang +15 more
wiley +1 more source
Non-Markovian Electron Transfer in Ligand-Receptor Complexes: Insights from Non-Gaussian Anharmonic Baths. [PDF]
Haseeb MW, Toutounji M.
europepmc +1 more source
Structure‐guided missense mutations in the C. elegans AGE‐1/PI3Kinase catalytic subunit and its LET‐60/Ras‐binding interface reveal separable signaling outputs from the Ras‐bound PI3K complex. Enhanced canonical catalytic activity, conferred by a gain‐of‐function mutation modeled on oncogenic human p110⍺ PI3K variants, promotes aging, reproductive ...
You Wu +4 more
wiley +1 more source
On certain novel numerical and analytical solutions for the pure-cubic Schrödinger equation in optical fibers with Kerr nonlinearity. [PDF]
Tariq KU +3 more
europepmc +1 more source
The structure of intact and active Photosystem II from Arabidopsis thaliana at 2.44 Å resolution
Summary Photosystem II (PS II) is a large membrane‐bound protein complex that catalyses light‐driven water oxidation in plants and cyanobacteria. The structure of PS II is well studied in cyanobacteria; however, there are very few PS II structures from plants.
Jack Forsman +6 more
wiley +1 more source

