Results 191 to 200 of about 19,010 (265)

Retraction notice to "Soliton dynamics in optical fiber based on nonlinear Schrödinger equation" [Heliyon 9 (2023) e14235]. [PDF]

Heliyon
Abdillah Mardi H, Nasaruddin N, Ikhwan M, Nurmaulidar N, Ramli M.   +4 more
europepmc   +1 more source

Synthesis, Anticancer Evaluation, mRNA Expression Analysis, and Molecular Docking of Fluorinated Picolinamide–Benzothiazole Derivatives Against Breast Cancer‐Related Genes CDK2, ERK2, and BCL2

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The graphical abstract summarizes the synthesis of novel benzothiazole‐linked derivatives and their biological evaluation. The compounds exhibited significant antioxidant activity, notable cytotoxic effects against MDA‐MB‐231 cells, apoptosis induction with G2/M arrest, gene regulation, and favorable molecular docking interactions, supporting their ...
Nagalakshmamma Vadabingi, Venkataswamy Mallepogu, Surendra Pothuraju, Chiranjeevi Pasala, Sumithra Poreddy, Uma Maheswari Amineni, Suresh Reddy Cirandur, Balaji Meriga   +7 more
wiley   +1 more source

Reliable numerical scheme for coupled nonlinear Schrödinger equation under the influence of the multiplicative time noise. [PDF]

Sci Rep
Baber MZ, Ahmed N, Yasin MW, Iqbal MS, Akgül A, Hassani MK, Jawaz M.   +6 more
europepmc   +1 more source

Soluble protein analog selection engine (SPASE): An automated AI‐powered server to improve protein engineering workflows

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The design of proteins with desired biophysical properties, such as high solubility and low aggregation propensity, is crucial for various biotechnological and biomedical applications. While deep learning‐based methods like ProteinMPNN have shown remarkable success in protein sequence design, their direct output may not always exhibit optimal ...
Sacha T. Larda, Alex Paré, Nicolas Doucet   +2 more
wiley   +1 more source

Investigation of soliton solutions to the (2 + 1)-dimensional stochastic chiral nonlinear Schrödinger equation with bifurcation, sensitivity and chaotic analysis. [PDF]

Sci Rep
Alqhtani M, Shahbaz A, Abbas M, Saad KM, Birhanu A, Yousaf MZ.   +5 more
europepmc   +1 more source

Investigating enzyme function by geometric matching of catalytic motifs

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The rapidly growing universe of predicted protein structures offers opportunities for data driven exploration but requires computationally scalable and interpretable tools. We developed a method to detect catalytic features in protein structures, providing insights into enzyme function and mechanism.
Raymund E. Hackett, Ioannis G. Riziotis, Martin Larralde, António J. M. Ribeiro, Georg Zeller, Janet M. Thornton   +5 more
wiley   +1 more source

Soliton solutions to the generalized derivative nonlinear Schrödinger equation under the effect of multiplicative white noise and conformable derivative. [PDF]

Sci Rep
Murad MAS, Mustafa MA, Younas U, Emadifar H, Khalifa AS, Mohammed WW, Ahmed KK.   +6 more
europepmc   +1 more source

A cryptic allosteric pocket shapes isoform‐selective inhibition of human malic enzymes

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Malic enzymes (ME) regulate central carbon metabolism and cellular redox balance, and the mitochondrial isoform ME2 is frequently upregulated in aggressive cancers to support metabolic flexibility and stress resistance. Isoform‐selective inhibition has remained out of reach because the catalytic machinery is essentially invariant across the ...
Ben A. Krinkel, Yuliana Yosaatmadja, Mark D. Slayton, Anita Krinkel, Jack Copping, Jin Heon Jeon, Joyce Eu, Kerslee Kohagen, Amir Ashoorzadeh, Jeff Smaill, Jack Flanagan, Christopher Walker, Sofia D. Merajver, Kerry Loomes, Christopher J. Squire   +14 more
wiley   +1 more source

Optical solitons, bifurcation, and chaos in the nonlinear conformable Schrödinger equation with group velocity dispersion coefficients and second-order spatiotemporal terms. [PDF]

Sci Rep
Omar FM, Murad MAS, Mahmood SS, Malik S, Radwan T.   +4 more
europepmc   +1 more source

Donor‐induced conformational gating and substrate‐assisted catalysis in α‐1,3‐galactosyltransferase

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Retaining glycosyltransferases catalyze the formation of stereochemically conserved glycosidic bonds through mechanisms that remain debated. Using bovine α1,3‐galactosyltransferase (α3GalT) as a model, we combine mutagenesis, equilibrium unfolding, kinetics, and molecular dynamics simulations to understand how donor‐induced loop ordering ...
Javier A. Linares‐Pastén, Antoni Planas   +1 more
wiley   +1 more source