Results 241 to 250 of about 106,917 (289)

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei, Mingyue Liuyuan, Zhixin Ye, Xueying Wang, Xueli Zhou, Yifan Shan, Cheng He, Chunting Zhu, Chicheng Zhou, Jingyin Bao, Yonghui Zhang, Gang Chen   +11 more
wiley   +1 more source

Decoding innate lymphoid cell heterogeneity and plasticity in colorectal cancer

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
This schematic outlines the origin, heterogeneity, and plasticity of ILCs in colorectal cancer. Created in BioRender. Yiyi, X. (2026) https://BioRender.com/0kwrvq7. Abstract Background In colorectal cancer (CRC), innate lymphoid cells (ILCs) play a vital role in preserving and modulating immune homeostasis within the intestinal environment.
Shuomin Zhang, Qingfeng Fu, Zhengyang Xu, Sijun Wang, Guoju You, Xiaoyu Su, Xiaotong Yuan, Chao Liu, Chen Liu, Chaojun Zhang, Bing Liu, Yandong Gong   +11 more
wiley   +1 more source

Myelin-Associated Glycoprotein in Myelin and Expressed by Schwann Cells Inhibits Axonal Regeneration and Branching

, 1998
Ying Shen, María Elena de Bellard, James L. Salzer, John Roder, Marie T. Filbin   +4 more
openalex   +1 more source

Glial-to-mesenchymal transition of tumor Schwann cells drives the genetic burden in MPNSTs from neurofibromatosis type 1 mouse model. [PDF]

Sci Adv
Radomska KJ, Onfroy A, Lecerf L, Job B, Beaude A, Sanz LS, El Jalkh T, Thieffry D, Charnay P, Wolkenstein P, Ortonne N, Coulpier F, Topilko P.   +12 more
europepmc   +1 more source

Circular RNAs as Biomarkers and Therapeutic Targets in Diabetic Cardiovascular Complications

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
This graphic abstract elaborates on the recent mechanism of circular RNAs (circRNAs) in the pathogenesis, diagnosis and treatment of diabetic cardiovascular complications. Diabetes mellitus induces oxidative/inflammatory stress, followed by endothelial dysfunction and leads to micro‐/macro‐vascular complications.
Shreya Singh Beniwal, Yujin Jeong, Akash Rawat, Mahmoud Einieh, Kashyapi Patil, Rafael Everton Assunção Ribeiro da Costa, Pulkit Saini, Kamal Yousef Ghazal, Abhijeet Kumar, Ayush Dwivedi, Anuja Anil Mandavkar   +10 more
wiley   +1 more source

Schwann cells modified to secrete MANF is a potential cellular therapy for peripheral nerve regeneration. [PDF]

Cell Regen
Sivakumar B, Hammond C, Martinez V, Joseph N, John JV, Kumar A, Krishnan A.   +6 more
europepmc   +1 more source

Integrated Single Cell Spatial Analysis Reveals Dysregulated Basal Progenitor Cells in Ulcerative Colitis Pathogenesis: A Multi Omics Study

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Ulcerative colitis (UC), a chronic inflammatory bowel disease, causes persistent mucosal inflammation and epithelial dysfunction. Basal progenitor cells (BPCs), critical for intestinal regeneration and mucosal repair, exhibit altered behavior in UC.
Xiaopeng Chen, Chuiguo Huang, Zhuofeng Wen, Weixuan Liang, Haobin Zhou, Zhiyi Zhou, Songan Li, Jianyang Guo, Naijun Yuan, Wanzhe Liao   +9 more
wiley   +1 more source

Differentially promoted peripheral nerve regeneration by grafted Schwann cells over-expressing different FGF-2 isoforms

, 2005
Kirsten Haastert‐Talini, Esther Lipokatic ́, Martin Fischer, Marco Timmer, Claudia Grothe   +4 more
openalex   +2 more sources

Optogenetic and Endogenous Modulation of Ca²⁺ Signaling in Schwann Cells: Implications for Autocrine and Paracrine Neurotrophic Regulation. [PDF]

Int J Mol Sci
Numata T, Tsutsumi M, Sato-Numata K.
europepmc   +1 more source

Successful Robot‐Assisted Resection of a Retroperitoneal Cystic Tumor With Fluorescent Ureteral Stent and Firefly Imaging

IJU Case Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Introduction We present a technique that combines a fluorescent ureteral catheter with Firefly near‐infrared fluorescence imaging to identify the ureter and avoid injury during robot‐assisted resection of a retroperitoneal cystic tumor. Case Presentation Computed tomography revealed a 6‐cm retroperitoneal cystic mass anterior to the abdominal ...
Yoichiro Tohi, Kana Kohashiguchi, Kenichi Tanaka, Mari Jinno, Takuma Kato, Rikiya Taoka, Nobufumi Ueda, Reiji Haba, Yoshihiro Nishiyama, Mikio Sugimoto   +9 more
wiley   +1 more source