Results 101 to 110 of about 280,960 (341)

Swiss CRM 2012 : Einsatz und Trends in Schweizer Unternehmen [PDF]

open access: yes, 2012
StudieDie jährlich und dieses Jahr bereits zum sechsten Mal durchgeführte Trendstudie bietet einen umfassenden Überblick zum Status Quo von Customer Relationship Management (CRM) in der Schweiz und identifiziert die bedeutendsten Trends.
Beerli, Beata   +4 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Flow-augmentation STA-MCA bypass for acute and subacute ischemic stroke due to internal carotid artery occlusion: the role of advanced neuroimaging in the decision-making

open access: yesBrain and Spine, 2023
Martina Sebök   +8 more
doaj   +1 more source

Sprachwandel und Sprachgeographie : der Einfluss der Stadt Bern auf die Region [PDF]

open access: yes, 2010
Bern, bis ins 18. Jh. Zentrum der regionalen Großmacht, heute mit nicht ganz 130.000 Einwohnern die viertgrößte Stadt der Schweiz und seit 1848 die Hauptstadt der Schweiz. Auf Grund dieser Ausgangslage würde man erwarten, dass Bern wie andere Städte eine
Siebenhaar, Beat
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Verbände in Deutschland: Potenzial und Relevanz für den Meeting-Markt Schweiz [PDF]

open access: yes, 2018
Grosse Verbandskongresse bringen einem Standort Wertschöpfung und Ansehen, fördern neben den ökonomischen Effekten aber auch den Wissenstransfer in einer Region. Sie fungieren als Schaufenster für die regionale Ökonomie und Wissenschaft.
Banz, Samira, Wilk, Rolf
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

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