Results 81 to 90 of about 282,906 (343)

Einkommensverhältnisse der freien Ärzteschaft der Schweiz in den Jahren 2005 (neu) und 2004 (Re-Evaluation) [PDF]

open access: bronze, 2009
Niklaus Hasler   +4 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Gleichheit durch individuelle Lösungen? Betriebliche Folgen des Wirtschaftsnutzendiskurses in der aktuellen schweizerischen Gleichstellungspolitik

open access: yesGender, 2014
Der Beitrag beleuchtet Mechanismen, die geschlechtsspezifische (Un-)Gleichheit in Unternehmen fördern. Dabei interessiert das Zusammenspiel von innerbetrieblichen Vorstellungen und dem dominierenden Diskurs der aktuellen schweizerischen ...
Lucia Marina Lanfranconi
doaj   +1 more source

Rückstandsrisiken von Pendimethalin - Abklärungen zur Situation in der Schweiz [PDF]

open access: yes, 2019
In dieser Studie soll ausfindig gemacht werden, ob Pendimethalin für Bioproduzenten in der Schweiz ein besonderes Kontaminationsrisiko darstellt, so wie im oben beschriebenen Fall mit Staudensellerie, Fenchel und Grünkohl.
Bögli, Sarah   +2 more
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Flow-augmentation STA-MCA bypass for acute and subacute ischemic stroke due to internal carotid artery occlusion: the role of advanced neuroimaging in the decision-making

open access: yesBrain and Spine, 2023
Martina Sebök   +8 more
doaj   +1 more source

Extraterritorialität im Bereich Wirtschaft und Menschenrechte: Extraterritoriale Rechtsanwendung und Gerichtsbarkeit in der Schweiz bei Menschenrechtsverletzungen durch transnationale Unternehmen [PDF]

open access: yes, 2016
Schweizer Unternehmen können an Menschenrechtsbeeinträchtigungen im Ausland beteiligt sein. Entweder direkt durch Aktivitäten im Ausland oder in der Schweiz mit Auswirkungen im Ausland oder indirekt, wie beispielsweise durch Tochtergesellschaften ...
Blattner, Charlotte   +3 more
core   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

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