Results 61 to 70 of about 89,270 (291)

Once‐Daily Oxycodone Prolonged‐Release Tablets Are Resistant to Alcohol‐Induced Dose Dumping: Results From a Randomized Trial in Healthy Volunteers

Clinical and Translational Science, 2020
The objective of this study was to determine the effect of concomitant alcohol intake on the bioavailability of oxycodone from an oxycodone once‐daily (OOD) formulation and an oxycodone twice‐daily (OTD) formulation.
Nils Burger, Douglas Fraser, Martina Alice Maritz, Janice Faulkner, Helene Rey   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Willkommen in der Nationalparkregion Sächsisch-Böhmische Schweiz

Mit dem Nationalpark bildet das Landschaftsschutzgebiet die Nationalparkregion Sächsische Schweiz. Hier bieten vielgestaltige Lebensräume zwischen Elbtal und Tafelbergen nicht nur Tieren und Pflanzen, sondern auch dem Menschen Raum zur Entfaltung.
Nagel, Richard, Mayr, Hanspeter, Klingner, Susanne   +2 more
core   +2 more sources

"Schweiz behagar mig mycket." Om Gunnar Serner och Schweiz

, 2023
Uppsatsen behandlar Gunnar Serners/Frank Hellers relation till Schweiz under perioden 1915―47, och skisserar tillkomsten och mottagandet av hans sista opus, Resa i Schweiz.
Hedman, Dag,
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Vineyard Leaf Canopy Management: Timing of the First Hedge-Trimming

IVES Technical Reviews
Delaying the date of the first hedge-trimming (or ‘tip-pruning’) is of limited technical value in vineyard canopy management. The impact of the delay on lateral shoot growth and must composition remains marginal within the context of the La Côte ...
Thibaut Verdenal, Jean-Laurent Spring, Ágnes Dienes-Nagy, Stefan Bieri, Vivian Zufferey   +4 more
doaj   +1 more source

Yield losses in vegetable and arable crops caused by yellow nutsedge (Cyperus esculentus) in farmers fields in Switzerland

Julius-Kühn-Archiv, 2018
Cyperus esculentus has become a serious weed in Switzerland. Despite intensive awareness training unaffected farmers tend to underestimate the consequences of C. esculentus infestation, especially the potential yield losses.
René Total, Lutz Collet, Jonathan Heyer, Martina Keller   +3 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source