Results 31 to 40 of about 257,634 (292)
Congruence of chloroplast- and nuclear-encoded DNA sequence variations used to assess species boundaries in the soil microalga Heterococcus (Stramenopiles, Xanthophyceae). [PDF]
, 2013 BackgroundHeterococcus is a microalgal genus of Xanthophyceae (Stramenopiles) that is common and widespread in soils, especially from cold regions. Species are characterized by extensively branched filaments produced when grown on agarized culture medium.
Andersen, Robert A +3 more
core +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
, 2007 Dank der Zusammenarbeit von elf europäischen Ländern im ERA-NET CORE Organic kam Transparenz in die Bio-Landbauforschung. Wie sieht die Situation in Deutschland, Österreich und der Schweiz aus?
Niggli, Urs, Willer, Helga
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Fence and plough for Lapwings: Nest protection to improve nest and chick survival in Swiss farmland [PDF]
, 2013 Switzerland had up to 1000 Lapwing pairs breeding in the 1970s. Actually, there are some 200. The crash was mainly due to a poor productivity of 0.2 to 0.4 fledglings per pair and year.
Koller, Andreia +2 more
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Technologie, Innovation und Entrepreneurship in der Schweiz: Eine Standortbestimmung [PDF]
, 2004 Technologie, Innovation und Entrepreneurship haben in den letzten Jahren an Bedeutung für das Wirtschaftswachstum gewonnen. Vor dem Hintergrund der aktuellen Wachstumsschwäche der schweizerischen Volkswirtschaft wird in dieser Arbeit die Schweiz ...
Mohr, Thomas
core
Zukunftsstudie : Elektromobilität Schweiz 2030 [PDF]
, 2013 StudieNoch fristet der Markt für Elektromobilität in der Schweiz ein Nischendasein, doch er scheint sich zunehmend zu formieren. Allerdings sind die langfristigen Unsicherheiten für die Beteiligten gross.
Cometta, Claudio +2 more
core +1 more source