Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]
Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky +6 more
core +2 more sources
Sciatic neuropathy with preserved sensory nerve action potentials, a case series [PDF]
Background: Sciatic neuropathy is differentiated from lumbosacral radiculopathy based on the finding of abnormal sensory nerve action potentials (SNAPs). Cases of sciatic neuropathy with intact SNAPS have not been well described. Methods: A retrospective
Li, Yuebing +2 more
core +2 more sources
Gpr126/Adgrg6 has Schwann cell autonomous and nonautonomous functions in peripheral nerve injury and repair [PDF]
Schwann cells (SCs) are essential for proper peripheral nerve development and repair, although the mechanisms regulating these processes are incompletely understood.
Carlin, Dan +8 more
core +2 more sources
Studies have confirmed that bone marrow-derived mesenchymal stem cells (MSCs) can be used for treatment of several nervous system diseases. However, isolation of bone marrow-derived MSCs (BMSCs) is an invasive and painful process and the yield is very ...
Marcela Fernandes +7 more
doaj +1 more source
Continuous sciatic nerve block [PDF]
Summary A technique of continuous sciatic nerve block is described. The method was used to relieve pain from ischaemic gangrene of the foot for 2 days before below‐knee amputation and, combined with a continuous inguinal paravascular block, to provide regional anaesthesia both for the surgery and for the first 2 postoperative days.
B E, Smith, H B, Fischer, P V, Scott
openaire +2 more sources
Interfacing peripheral nerve with macro-sieve electrodes following spinal cord injury [PDF]
Macro-sieve electrodes were implanted in the sciatic nerve of five adult male Lewis rats following spinal cord injury to assess the ability of the macro-sieve electrode to interface regenerated peripheral nerve fibers post-spinal cord injury. Each spinal
Birenbaum, Nathan K +2 more
core +3 more sources
Reduced axonal diameter of peripheral nerve fibres in a mouse model of Rett syndrome [PDF]
Rett syndrome (RTT) is a neurological disorder characterized by motor and cognitive impairment, autonomic dysfunction and a loss of purposeful hand skills.
Bahey, Noha G. +5 more
core +1 more source
Unique Formation of Sciatic Nerve Below the Piriformis Muscle – A Case Report [PDF]
Dorsal and ventral divisions of ventral rami of lower lumbar and sacral spinal nerve were found to pass ventral and dorsal to the piriformis muscle respectively. These divisions joined each other below the piriformis muscle to form sciatic nerve.
Jyothsna Patil +4 more
doaj +1 more source
Lack of evidence for sprouting of Aβ afferents into the superficial laminas of the spinal cord dorsal horn after nerve section [PDF]
The central arborizations of large myelinated cutaneous afferents normally extend as far dorsally as the ventral part of lamina II in rat spinal cord. Woolf et al. (1992) reported that after nerve injury some of these afferents sprouted into lamina I and
Hughes, D.I. +3 more
core +1 more source
Measuring neuromuscular junction functionality [PDF]
Neuromuscular junction (NMJ) functionality plays a pivotal role when studying diseases in which the communication between motor neuron and muscle is impaired, such as aging and amyotrophic lateral sclerosis (ALS).
Del Prete, Zaccaria +4 more
core +1 more source

