Results 31 to 40 of about 413,709 (291)

Analysis of the C/EBP family of transcription factors in neuronal repair [PDF]

, 2009
PhDNeurons within the peripheral nervous system (PNS) have a remarkable ability to repair themselves after injury; however, neurons within the central nervous system (CNS) do not spontaneously regenerate.
López de Heredia, Luis
core   +3 more sources

Silencing of circRNA.2837 Plays a Protective Role in Sciatic Nerve Injury by Sponging the miR-34 Family via Regulating Neuronal Autophagy

Molecular Therapy: Nucleic Acids, 2018
Circular RNAs (circRNAs) represent a class of non-coding RNAs that are involved in transcriptional and posttranscriptional gene expression regulation and associated with different kinds of human diseases.
Zhi-bin Zhou, Yu-long Niu, Gao-xiang Huang, Jia-jia Lu, Aimin Chen, Lei Zhu   +5 more
doaj   +1 more source

Biomimetic chitosan scaffolds with long-term controlled release of nerve growth factor repairs 20-mm-long sciatic nerve defects in rats

Neural Regeneration Research, 2022
Although autogenous nerve transplantation is the gold standard for treating peripheral nerve defects of considerable length, it still has some shortcomings, such as insufficient donors and secondary injury.
Fa-Dong Liu, Hong-Mei Duan, Fei Hao, Wen Zhao, Yu-Dan Gao, Peng Hao, Zhao-Yang Yang, Xiao-Guang Li   +7 more
doaj   +1 more source

Surgically Induced Demyelination in Rat Sciatic Nerve

, 2023
Demyelination is a common sign of peripheral nerve injuries (PNIs) caused by damage to the myelin sheath surrounding axons in the sciatic nerve. There are not many methods to induce demyelination in the peripheral nervous system (PNS) using animal models.
Rahul Shankar Rao Rayilla, Phanithi Prakash Babu, MUR Naidu   +2 more
core   +1 more source

A Rabbit Model for Peripheral Nerve Reconstruction Studies Avoiding Automutilation Behavior

Journal of Brachial Plexus and Peripheral Nerve Injury, 2022
Background The rabbit sciatic nerve injury model may represent a valuable alternative for critical gap distance seen in humans but often leads to automutilation. In this study, we modified the complete sciatic nerve injury model for avoiding autophagy.
Jonathan A. Sorkin, Ziv Rechany, Mara Almog, Nina Dietzmeyer, Yuval Shapira, Kirsten Haastert-Talini, Shimon Rochkind   +6 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics

Advanced Functional Materials, EarlyView.
Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley   +1 more source

Nerve stimulator-guided sciatic-femoral nerve block in raptors undergoing surgical treatment of pododermatitis. [PDF]

, 2014
OBJECTIVE To describe the nerve stimulator-guided sciatic-femoral nerve block in raptors undergoing surgical treatment of pododermatitis. STUDY DESIGN Prospective clinical trial. ANIMALS Five captive raptors (Falco peregrinus) aged 6.7 ± 1.
Noviello, E, Noviello, Emilio, D'Ovidio, D, d'Ovidio, Dario, Adami, C, Adami, Chiara, Noviello E, d'Ovidio D, Adami C   +8 more
core   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Role of high-resolution ultrasound in assessment of iatrogenic sciatic nerve injury in pediatric age group in correlation with electrophysiological studies. [PDF]

Ain Shams Medical Journal
Background: The sciatic nerve is among the largest peripheral nerves in terms of thickness within the body. Injecting the gluteal muscles can lead to an iatrogenic issue known as sciatic nerve injury, which can result in notable health complications.
Mary Abadir, Hanan Arafa, Soad El Molla, Noha Gamal El Deen   +3 more
doaj   +1 more source